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  1. Jan 18, 2012 · We propose that medical therapy should be used to stabilize the patient and to adequately assess the degree of SAM and MR. If there is only mild SAM and MR, then medical therapy should be used. However, in moderate or worse SAM and MR, we propose that even if medical therapy is able to abolish SAM, a surgical solution should be sought.

    • Michael Ibrahim, Christopher Rao, Hutan Ashrafian, Umar Chaudhry, Ara Darzi, Thanos Athanasiou
    • 2012
  2. Apr 1, 2012 · Objective. To evaluate the effectiveness and outcomes of an intraoperative and postoperative algorithm for managing systolic anterior motion (SAM) after mitral valve repair (MVRr). Methods. All consecutive patients who underwent MVRr for degenerative disease from January 2002 to June 2011 were included, with the data collected retrospectively.

    • Robin Varghese, Anelechi C. Anyanwu, Shinobu Itagaki, Federico Milla, Javier Castillo, David H. Adam...
    • 2012
  3. rection of SAM, irrespective of the response to medical interventions. If mild SAM is present, defined as less than mild MR and a LVOT gradient of less than 50 mm Hg, we usually use no additional surgical intervention and proceed to reversal of heparin and decannulation. An echocardiogram

  4. Aug 22, 2023 · Optimal guideline-directed medical therapy is the mainstay therapy and has been shown to reduce the severity of mitral regurgitation in 40–45% of patients. Rapid medication titration protocols reduce heart failure hospitalisation and facilitate earlier referral for device therapy.

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  6. Sep 21, 2023 · Mucuna pruriens ( M. pruriens) is a vegetable plant native to tropical and subtropical regions of Africa, South America, and Asia. It is a part of the Fabaceae family and is one of many species of Mucuna. M. pruriens is commonly referred to as velvet bean or cowhage. M. pruriens is classified as a legume.

  7. Apr 5, 2016 · The guidelines state that treatment programs for SAM should achieve a CFR of less than 10 percent, a recovery rate greater than 75 percent, and a defaulter rate of less than 15 percent (Sphere Project 2011).

  8. With most SAM treatment now being in the outpatient setting, broad-spectrum oral antibiotics for uncomplicated SAM continue to be recommended by WHO and UNICEF. For complicated SAM, intravenous therapy followed by oral therapy (including a prolonged course of an amino-glycoside) is recommended; however, the evidence base

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