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    • Image courtesy of researchgate.net

      researchgate.net

      • The recognized benefits of inflammation to the CNS include the preservation of CNS constituents (neuroprotection), the proliferation and maturation of various neural precursor populations, axonal regeneration, and the reformation of myelin on denuded axons.
      www.nature.com/articles/s41423-019-0223-3
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  2. Jul 1, 2019 · The choice of neuroinflammation as the theme for the 5th European Academy of Neurology Congress in 2019 and of this Focus issue highlights its importance to neurologists across the discipline.

    • Nature

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  3. Introduction to Neuroinflammation. Neuroinflammation is defined as an inflammatory response within the brain or spinal cord. This inflammation is mediated by the production of cytokines, chemokines, reactive oxygen species, and secondary messengers.

  4. Feb 1, 2014 · Neuroinflammation is central to the common pathology of diseases/disorders. Neuroinflammation causes acute brain cell death. Neuroinflammation causes and accelerates long-term neurodegenerative disease. Preventative and therapeutic approaches are needed to dampen-down neuroinflammation.

    • Monty Lyman, Dafydd G. Lloyd, Xunming Ji, Marcela P. Vizcaychipi, Daqing Ma
    • 2014
  5. Mar 15, 2019 · The recognized benefits of inflammation to the CNS include the preservation of CNS constituents (neuroprotection), the proliferation and maturation of various neural precursor populations, axonal...

    • Heather Y F Yong, Khalil S Rawji, Samira Ghorbani, Mengzhou Xue, V Wee Yong
    • 2019
  6. This review examines the consequences of excessive and prolonged neuroinflammation, particularly its damaging effects on cellular and/or brain function, as well as its relevance to disease progression and possible interventions.

    • Monty Lyman, Dafydd G. Lloyd, Xunming Ji, Marcela P. Vizcaychipi, Daqing Ma
    • 2014
  7. Jul 12, 2023 · In this review, we mainly focus on the relationship between neuroinflammation and the pathology of neurodegenerative diseases, the vital inflammatory signaling pathways involved neurodegeneration...

  8. Inflammation can be especially perilous where the nervous system is involved (so-called “neuroinflammation”), whether it be of an acute nature or chronic—the latter involving sustained activation of glia and recruitment of immune elements.

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