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- The year 2016 marks 100 years since the death of Élie Metchnikoff (1845–1916), the Russian zoologist who pioneered the study of cellular immunology and who is widely credited with the discovery of phagocytosis, for which he was jointly awarded the Nobel Prize in Physiology or Medicine in 1908.
www.nature.com/articles/nri.2016.89
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Élie Metchnikoff was a Russian-born zoologist and microbiologist who received (with Paul Ehrlich) the 1908 Nobel Prize for Physiology or Medicine for his discovery in animals of amoeba-like cells that engulf foreign bodies such as bacteria—a phenomenon known as phagocytosis and a fundamental part.
- The Editors of Encyclopaedia Britannica
Aug 1, 2016 · The year 2016 marks 100 years since the death of Élie Metchnikoff (1845–1916), the Russian zoologist who pioneered the study of cellular immunology and who is widely credited with the discovery...
- David M. Underhill, Siamon Gordon, Beat A. Imhof, Gabriel Núñez, Philippe Bousso
- 2016
Metchnikoff discovered fungal infections causing insect death in 1879 and became involved in the biological control of insect pests through his student Isaak Krasilschik. They were able to make use of green muscardine for control of insects in agricultural fields.
Jun 16, 2016 · Since Metchnikoff’s era, significant contributions from the scientific community have brought considerable knowledge to the immunology arena, shedding a new light on innate and adaptive immunities that have become more complementary and integrated in the host resistance to infectious diseases.
- Fabrice Merien
- 10.3389/fpubh.2016.00125
- 2016
- Front Public Health. 2016; 4: 125.
As a vigorous proponent of cellular immunity, he championed its importance versus humoral immunity in the so-called antibody wars. By 1908, when the Nobel Prize was awarded to Elie Metchnikoff and Paul Ehrlich, this debate was not yet resolved.
- Siamon Gordon
- 2016
Metchnikoff is rightly famous for his recognition of the biological significance of leukocyte recruitment and phagocytosis of microbes in host defence against infection, inflammation and immunity. As a comparative zoologist he utilised a broad range of model organisms for microscopic studies in vivo and in vitro.
Jul 1, 2008 · Metchnikoff discovered phagocytosis by macrophages and microphages as a critical host-defense mechanism and thus is considered the father of cellular innate immunity.