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Laboratory mice are the same species as the house mouse; however, they are often very different in behaviour and physiology. There are hundreds of established inbred, outbred, and transgenic strains. A strain, in reference to rodents, is a group in which all members are as nearly as possible genetically identical.
Laboratory rats or lab rats are strains of the rat subspecies Rattus norvegicus domestica (Domestic Norwegian rat) which are bred and kept for scientific research. While less commonly used for research than laboratory mice, rats have served as an important animal model for research in psychology and biomedical science. [1]
Why do we use rats? The laboratory rat has made invaluable contributions to cardiovascular medicine, neural regeneration, wound healing, diabetes, transplantation, behavioural studies and space motion sickness research. Rats have also been widely used to test drug efficacy and safety.
Nov 16, 2010 · Mice and rats make up 95 percent of all animals used in medical research, from drug development to testing dietary supplements. Life's Little Mysteries explains what makes these rodents the ideal...
Jul 14, 2021 · Rats are obviously larger – about ten times the size of a lab mouse – but they are also more social animals and can be quicker to pick up more complex tasks.
- Ellen P. Neff
- ellen.neff@us.nature.com
- 2021
Feb 27, 2019 · Due to their genetic and physiological similarities to humans, lab rodents have become the cornerstone of animal research. Olena Kurashova/iStock. More than 20 years ago, two Harvard University...
Feb 25, 2022 · Mice and rats make up nearly 99% of animals used in research. But how did medical research come to be so dependent on these tiny rodents? How exactly do scientists genetically engineer mice to be suitable to study pretty much any human ailment? And why do the majority of medicines that are effective in mice fail in humans?
