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  1. The Ascending Reticular Activating System (ARAS) is defined as a diverse system in the brainstem that projects to the diencephalon and cortex, responsible for producing activation seen in waking and dreaming states through changes in brain wave frequency and amplitude. AI generated definition based on: Encyclopedia of Behavioral Neuroscience, 2010

  2. Neuroanatomically, the ascending reticular activating system (ARAS) and related structures responsible for arousal are primarily located in the brainstem in the paramedian tegmental grey matter immediately ventral to the pons. Three ARAS principle pathways have been identified (Figure 58-1).

  3. We found that the human ARAS shares several important features with that of experimental animals: 1) ARAS brainstem source nuclei connect primarily with the intralaminar, paraventricular, and reticular nuclei of the thalamus; 2) the known monoaminergic-, cholinergic-, and glutamatergic-related nuclei in the upper brainstem all connect with the ...

  4. Jul 24, 2013 · The rostral portion of the RF of the brainstem above the trigeminal nerve entry zone is known as the ARAS; in contrast, the caudal portion of the RF is involved in motor function and autonomic function related to cardiac and respiratory function (Daube, 1986).

  5. Feb 22, 2019 · The ARAS influences autonomic regulation of respiration, heart rate and blood pressure. The rostral portion of the pons (about midway and up) regulates wakefulness. A bilateral lesion of the tegmentum (and, likely, extending into the medial portion of the brainstem) is needed to affect its function.

    • Eelco F M Wijdicks
    • wijde@mayo.edu
    • 2019
  6. Discovery of the ascending reticular activating system (ARAS) can be attributed to work done in research neuroscien-tist Horace Magoun’s laboratory. Before this finding, most scientists would focus on the diencephalon (and anterior midbrain) but not more caudally.

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  8. Jan 1, 2014 · The ARAS is not limited to the brain stem: it projects upwards towards the cerebral hemispheres and downwards towards the spinal cord. Its functions are much more complex than simple cortical...

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