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Maurice Hilleman. Maurice Ralph Hilleman (August 30, 1919 – April 11, 2005) was a leading American microbiologist who specialized in vaccinology and developed over 40 vaccines, an unparalleled record of productivity. [2][3][4][5][6] According to one estimate, his vaccines save nearly eight million lives each year. [3]
Aug 27, 2016 · When Hilleman died in 2005, after a truly magnificent scientific career of 60 years, Dr. Paul Offit, chief of infectious diseases at the Children’s Hospital of Philadelphia, told the BMJ: “His commitment was to make something useful and convert it to clinical use.
- Theodore H. Tulchinsky, Theodore H. Tulchinsky
- 10.1016/B978-0-12-804571-8.00003-2
- 2018
- 2018
- Vaccines
- Hilleman’S First Vaccine
- Preventing An Influenza Pandemic
- Dozens of New Vaccines
- New Discoveries
- Some Personal Details and The End
Maurice Hilleman was the greatest inventor of vaccines the world has ever known. His vaccines were based on the idea used by earlier scientists such as Louis Pasteur, that you could take a virus and weaken it. The virus would then be too weak to cause disease, but would push people’s immune systems into producing natural antibodies. These antibodie...
Hilleman joined the pharmaceutical company E. R. Squibb in New Jersey in 1944. He developed an effective vaccine against Japanese B encephalitis and worked on the mass production of influenza vaccine.
In 1948, age 28, Hilleman moved to Washington, D.C. to join the Department of Respiratory Diseases at Army Medical Center. There he became an authority on mutation in influenza viruses, observing two different mechanisms for genetic changes in influenza: drift, a gradual annual change in the virus; and shift, a less frequent but more dramatic chang...
In 1957, age 38, Hilleman was recruited by the pharmaceutical company Merck & Co. He moved to West Point, Pennsylvania, from where he would lead Merck’s virus and vaccination research programs for the next 45 years. At Merck he had unprecedented success, inventing a series of highly effect new vaccines to protect people against measles, mumps, rube...
Hilleman was the discoverer or co-discoverer of several viruses. These included hepatitis A, SV40, and a number of adenoviruses and rhinoviruses. He was the first scientist to purify the drug interferon and he discovered that interferon’s expression is induced by double-stranded RNA.
In 1943, age 23, Hilleman married Thelma Mason with whom he had two daughters, Jeryl Lynn and Kirsten. Thelma died in 1962. In 1963 Hilleman married Lorraine Witmer. Hilleman had a reputation as a tough and at times ill-tempered man. He worked seven-day weeks and expected people he directed at Merck to do likewise. Anyone who didn’t measure up to h...
May 29, 2020 · In 1957 a flu pandemic hit the U.S., but Maurice Hilleman was ready with a vaccine he mass produced in only months. In April 1957, a mysterious illness was making its way through Hong Kong ...
Thank you Dr. Hilleman for pushing through the tough times and finding a way to save millions. So many owe their lives to you.” - Gracie B., age 15, MO “Dr. Hilleman has saved a countless number of lives through his innovation, commitment, and compassion: he is a true hero.” - Alex S., age 17, GA
May 6, 2013 · An additional 20,000 suffered birth defects, including deafness, heart disease and cataracts. Dr. Hilleman was already testing his own vaccine as the epidemic ended in 1965. But he agreed to work ...
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Fall/19. Maurice Hilleman, PhD’44, was born in 1919 near Miles City, Montana, during the deadliest influenza pandemic in history. When the next global influenza pandemic arrived, Hilleman was in the position to save thousands of lives, thanks in part to his Montana roots. Before Hilleman, who died in April 2005, became the world’s most ...
