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    • Anthony Edwards played Dr. Mark Greene for eight seasons before leaving after his character—and this is a spoiler alert for a show that premiered more than 20 years ago—died from a brain tumor.
    • Noah Wyle's Dr. John Carter became the focus of the show when Edwards left, and Wyle stuck around for a few seasons later before departing, only to return more than once up until the end of the series.
    • Julianna Margulies' Carol Hathaway was supposed to die from an overdose in the pilot, but she tested well and Margulies stuck around. She became such a central figure she was offered more than $20 million to stick around—but she exited the series at the end of season six with a surprise appearance by Clooney.
    • Eriq La Salle stuck around Cook County General for eight seasons before exiting. However, his Dr. Peter Benton returned as a special guest in the final season.
  1. Apr 24, 2019 · Former ER star Noah Wyle has opened up about his time on the medical drama.. In a lengthy interview with The Hollywood Reporter, the star – who played Dr John Carter between 1994 and 2009 ...

    • jlee@digitalspy.com
  2. Sep 25, 2024 · ER turns 30! See where the cast is now, including George Clooney, Julianna Margulies, and more. Catch up on the latest with your favorite stars from the hit medical drama. (From left to right ...

  3. Feb 14, 2023 · Alex Kingston's exit from ER occurred in episodes 3 and 4 of season 11. Dr. John Carter convinces Corday to perform an illegal procedure on two patients with HIV, which puts her in peril of losing her medical license and being fired from Cook County Hospital. Although Dr. Kerry Weaver offers her a lesser position as a clinical instructor ...

    • Senior Staff Writer
  4. Sep 19, 2022 · Margulies left "ER" in season six, making every fan swoon when she finally reunited with Dr. Ross for good in the finale. Margulies won an Emmy for her role in "ER" in 1995, making her the only ...

    • Henry Blodget
  5. Sep 19, 2024 · Anthony Edwards. Photo : NBC/Everett Collection; Anna Moneymaker/Getty Images. Anthony Edwards, now 62, starred for eight seasons as Dr. Mark Greene; his character famously succumb to brain cancer ...

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  7. Sep 17, 2020 · ER was also well known for having an incredible ensemble cast, many of whom left the show for even higher levels of stardom. Yes, ER was quite the launching pad for quite a few stars. As the show ...

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