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Leader in breast cancer research
- Tony Howell has been a leader in breast cancer research at The Christie and Manchester University NHS Foundation Trusts and the University of Manchester for over 40 years.
www.mcrc.manchester.ac.uk/a-celebration-of-professor-tony-howells-academic-achievements/
Tony Howell’s contribution to medical science is in laboratory and clinical studies on the breast and in clinical science administration. He is responsible for introducing several new treatments which have improved patient outcome.
- Research Groups
Anthony Howell is Professor of Medical Oncology and, leads...
- News
Tony Howell has been a leader in breast cancer research at...
- Research Groups
Tony Howell has been a leader in breast cancer research at The Christie and Manchester University NHS Foundation Trusts and the University of Manchester for over 40 years. He played a key role in the development of paradigm-changing targeted drug therapies for breast cancer, such as tamoxifen, anastrozole and goserelin and the first in class ...
Anthony Howell is Professor of Medical Oncology and, leads the Genesis Prevention Centre Research Programme at the University Hospital of South Manchester NHS Foundation Trust. He is the former Director of the Breast Cancer Now Research Unit, and the Manchester Breast Centre.
- High-Risk Removal
- Trial by Tamoxiten
- Watch Out for...
- It Ain’T Over Till The Fat Lady Thins
- An Inflammatory Story
- Studying The Female Form
- Walk Away from Breast Cancer
- The Oldies of Okanawa
- The Next Steps
At the top of the Urgent list for preventative care, says Tony, must be those women who have three first-line family members (mother, sisters) with breast cancer, giving them a one-in-four - or greater - risk of developing the disease. At the Christie all women in this category are offered prophylactic mastectomy which some 10-15 per cent take up. ...
The quintessential scientist, Tony Howell stresses he won’t recommend any remedy that’s not backed up by randomised trials, If excessive hormone levels cause breast cancer, then might it not be possible suppress the levels medically? "Absolutely," says Tony Howell. "So much breast cancer is caused by oestrogen. We’ve therefore conducted a five year...
Gosarelin, an injected drug that switches off the periods of premenopausal women, and reduces their breast cancer risk by about 40 per cent. Tony explains that he is testing the effect of switching off the ovaries for two years to see if that’s enough to prevent subsequent breast cancer. "We have an ongoing study at the moment and we are also looki...
While the most striking remedy for high risk women is scientific, surgical and specific, prevention for the majority of women could depend on simple lifestyle changes. It turns out that women bent on shedding the kilos are not swayed mere foolish vanity, but doing themselves a vital favour. New date analysis, says the Prof, has shown that gaining t...
The breast cancer plague won’t be over, it seems, till the fat lady thins. But why, scientifically do cells change in fat? "We’re involved in new research to work out the mechanism" says Tony, "but the best working hypothesis is that as you get fat you develop inflammation in the fat stores. The inflammatory cells then make all sorts of nasty growt...
Tony Howell and Christie’s research dietitian, Michelle Harvie, have just completed a study on weight loss and exercise, which is currently still being analysed before the report stage. Women aged 3 5-45 who have lost weight are being checked for lower hormone levels and reduced density of breast tissue in mammograms. Early results are promising: h...
Apparently we need not go for the burn or the super-advanced step class at a fancy gym. Fourteen studies have shown that even moderate exercise - walking briskly or running gently for 30 minutes five times a week reduces breast cancer. Says Tony Howell, "It looks as if a five per cent weight loss coupled with two and a half hours of exercise a week...
Slimming your way out of cancer sounds so simple. But how often does a busy clinician like Tony Howell manage to get the message across to his patients? "I tell them a lot, actually" he stresses, "because honestly, eating healthily isn’t hard, it’s easy. Look at me! I know what’s good for me, so on the whole I avoid animal fat and I try and eat les...
"We may want to find ways to clock the effects of obesity, possibly blocking Coxl and Cox2, the enzymes that stop you producing prostaglandins which in turn produce inflammation. We need better ways to define women at high risk of cancer because the genetic link only affects some 5-10 per cent. Looking at a woman’s age of menopause, first pregnancy...
Aug 11, 2004 · Tony Howell, professor of Medical Oncology at Christie, Withington and Wythenshawe hospitals, is pioneering the trial of the drug which experts believe could halve the number of victims.
Tony Howell, founder of the Family History Clinic. In the 1980s, the rising incidence of breast cancer (BC) and the introduction in the UK of the NHS National Health Service Breast Screening Programme (NHSBSP) led women with a family history of the disease to seek advice concerning management of their personal risk. .
Jul 3, 2023 · Tony Howell has been a leader in breast cancer research at The Christie and Manchester University NHS Foundation Trusts and the University of Manchester for over 40 years. He played a key role in the development of paradigm-changing targeted drug therapies for breast cancer, such as tamoxifen, anastrozole and goserelin and the first in class ...
