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    • Physician John Haygarth

      • The first to recognize and demonstrate the placebo effect was English physician John Haygarth in 1799. He tested a popular medical treatment of his time, called "Perkins tractors", which were metal pointers supposedly able to 'draw out' disease.
      en.wikipedia.org/wiki/Placebo_in_history
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  2. Placebo is the opening word of the antiphon of vespers in the Office of the Dead, used as a name for the service as a whole. The full sentence, from the Vulgate, is Placebo Domino in regione vivorum 'I will please the Lord in the land of the living', from Psalm 116:9.

  3. In the 18th century those physicians who prescribed placebo usually thought of drugs which were considered not very effective in the particular case, e.g. a mild ointment. At the same time, only very few brilliant minds came up with the ingenious idea of using inert substances as placebo.

    • Robert Jütte
    • 2013
  4. Placebo is a British alternative rock band, formed in London in 1994 by vocalistguitarist Brian Molko and bassist–guitarist Stefan Olsdal, and in late 1994 Robert Schultzberg joined as drummer.

    • From Pleasing Prayers to Pleasing Treatments
    • Placebos in Clinical Trials
    • Placebo Surgery
    • Honest Placebos
    • The History of Learning How Placebos Work
    • History of Placebo Ethics
    • Whither Placebo?

    The word “placebo”, as it is used in medicine, was introduced in Saint Jerome’s fourth-century translation of the Bible into Latin. Verse 9 of Psalm 114 became: placebo Domino in regione vivorum. “Placebo” means “I will please”, and the verse was then: “I will please the Lord in the land of the living.” Historians are keen to point out that his tra...

    Placebos were first used in clinical trials in the 18th century to debunk so-called quack cures. Which is paradoxical because the so-called “non-quack” cures at the time included bloodletting and feeding patients the undigested material from the intestines of an oriental goat. These were considered to be so effective that no trials were needed. The...

    Recently, placebo-controlled surgery trials have been used. In perhaps the most famous of these, American surgeon Bruce Moseley found 180 patients who had such severe knee pain that even the best drugs had failed to work. He gave half of them real arthroscopy and the other half placebo arthroscopy. Patients in the placebo arthroscopy group were giv...

    A placebo can work even if a patient does not believe it is a “real” treatment. In the first of the studies of open-label placebos (placebos that patients know are placebos) I know of, two Baltimore doctors by the names of Lee Park and Uno Covi gave open-label placebos to 15 neurotic patients. They presented the placebo pills to the patients and sa...

    An early study investigating the inner pharmacology of placebo mechanisms is Jon Levine and Newton Gordon’s 1978 study of 51 patientswho had impacted molars extracted. All 51 patients had received a painkiller called mepivacaine for the surgical procedure. Then, at three and four hours after the surgery, the patients were given either morphine, a p...

    The accepted view in clinical practice is that placebos are not ethical because they require deception. This view has not yet fully accounted for the evidence that we don’t need deception for placebos to work. The history of the ethics of placebo controls is more complex. Now that we have many effective treatments, we can compare new treatments wit...

    For centuries, the word “placebo” was closely linked to deception and pleasing people. Recent studies of open-label placebos show that they need not be deceptive to work. Contrariwise, studies of placebos show that they are not inert or invariable and the basis for the current World Medical Association position has been undermined. The recent histo...

  5. en.wikipedia.org › wiki › PlaceboPlacebo - Wikipedia

    A placebo (/ p l ə ˈ s iː b oʊ / plə-SEE-boh) can be roughly defined as a sham medical treatment. [1] Common placebos include inert tablets (like sugar pills), inert injections (like saline), sham surgery, [2] and other procedures. [3] Placebos are used in randomized clinical trials to test the efficacy of medical treatments.

  6. Apr 1, 2013 · The letter proves that as early as the beginning of the 19th century physicians consciously used the placebo effect while being aware of the ethical implications (“pious fraud”). Explaining the placebo effect: early attempts. Recent research suggests that expectancy is an integral part of the placebo effect.

  7. The first section reconstructs the etymology of the term "placebo" and its first introduction in medicine. The next sections provide an account of how placebos have been employed in both medical practice and scientific research in modern medicine.

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