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  1. Tumor Necrosis Factors. The development of skin appendages such as hairs, teeth, and mammary glands is regulated by signaling molecules of the Wnt, FGF, TGFbeta, and Hedgehog pathways. Last decade has also revealed a pivotal role for the TNF family ligand ectodysplasin (Eda) in multiple steps of epithelial appendage morpho ….

  2. Jun 1, 2008 · Abstract. The development of skin appendages such as hairs, teeth, and mammary glands is regulated by signaling molecules of the Wnt, FGF, TGFβ, and Hedgehog pathways. Last decade has also revealed a pivotal role for the TNF family ligand ectodysplasin (Eda) in multiple steps of epithelial appendage morphogenesis, from initiation to ...

    • Marja L. Mikkola
    • 2008
  3. Apr 24, 2023 · The skin appendages are epidermal and dermal-derived components of the skin that include hair, nails, sweat glands, and sebaceous glands. Each component has a unique structure, function, and histology. This article describes the unique characteristics of each of these components and provides insight into tissue preparation for microscopic evaluation and the clinical significance of these ...

    • Hani Yousef, Julia H. Miao, Mandy Alhajj, Talel Badri
    • 2023/04/24
    • 2020
  4. Nov 14, 2018 · The expansion of pathogenic bacteria and fungi in skin appendages easily stimulates neighbouring keratinocytes to produce inflammatory cytokines and chemokines that can recruit neutrophils and ...

    • Kenji Kabashima, Kenji Kabashima, Tetsuya Honda, Florent Ginhoux, Florent Ginhoux, Gyohei Egawa
    • 2019
  5. The development of skin appendages such as hairs, teeth, and mammary glands is regulated by signaling molecules of the Wnt, FGF, TGFβ, and Hedgehog pathways. Last decade has also revealed a pivotal role for the TNF family ligand ectodysplasin (Eda) in multiple steps of epithelial appendage morphogenesis, from initiation to differentiation.

  6. Sep 1, 2017 · Moreover, the regeneration of skin appendages after severe injuries remains a challenge in treatment. Future Directions: Understanding epidermal stem cells and their essential functions during skin wound healing are fundamental components behind the development of clinical treatment on patients with cutaneous wounds. It is important to improve ...

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  8. Jun 1, 2008 · The development of skin appendages such as hairs, teeth, and mammary glands is regulated by signaling molecules of the Wnt, FGF, TGFbeta, and Hedgehog pathways.

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