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  1. 3. When to start PEP (section 8): PEP should be initiated as soon as possible after exposure, preferably within 24 hours. PEP should not be initiated beyond 72 hours after exposure. 4. Baseline tests (section 9): All exposures: 1. Creatinine (and eGFR) 2. Alanine transaminase 3. HIV-1 Ag/Ab 4.

  2. Aug 1, 2023 · Summary. Post-exposure prophylaxis for HIV must be initiated as soon as possible, ideally within 2 hours, and preferably within 24 hours of exposure. However, the period during which post-exposure prophylaxis (PEP) is most efficacious is often said to be within 72 hours of exposure. Most exposures have only a low risk of HIV transmission even ...

  3. 3. When to start PEP (Section 8) PEP should be initiated as soon as possible after expo-sure, preferably within 24 h. PEP should not be initiated beyond 72 h after exposure. 4. Baseline tests (Section 9) All exposures:

  4. Jul 22, 2024 · PEP is most effective when initiated as soon as possible, ideally within 24 hours and no later than 72 hours after exposure. While a PEP regimen of two drugs can be effective, three drugs are preferred. It is recommended that people be given a 28-day prescription for PEP. This guideline includes recommended drug regimens for adults, adolescents ...

  5. Oct 3, 2024 · If PEP is prescribed after 72 hours and then discontinued after 28 days, the risk of viral rebound with that inadvertent interruption in ART is significant, as is the associated risk of developing resistance to ART; therefore, this committee stresses that PEP should not be initiated later than 72 hours after exposure.

  6. Abstract. We present the updated British Association for Sexual Health and HIV (BASHH) guidelines for post-exposure prophylaxis (PEP) to HIV following sexual exposures, occupational exposures and other nonoccupational exposures in the community. This serves as an update to the 2015 BASHH guideline on PEP following sexual exposures and the 2008 ...

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  8. PEP involves administering antiretroviral (ARV) medication after potential HIV exposure to prevent infection. Timely access to PEP is the most crucial factor in PEP effectiveness. PEP is most effective when initiated as soon as possible, ideally within 24 hours and no later than 72 hours after exposure. While a PEP regimen of two drugs can be

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