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    • 20 years ago

      • MCI was introduced as a clinical entity more than 20 years ago, and since then, groups of individuals with this diagnosis have been intensively investigated from many perspectives including clinical, imaging, genetic, pathological and epidemiological 5.
      onlinelibrary.wiley.com/doi/full/10.1111/joim.12190

      Mild cognitive impairment: a concept in evolution - Petersen ...

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  3. onlinelibrary.wiley.com › doi › fullMild cognitive impairment: a concept in evolution - Petersen ...

    Mar 8, 2014 · The first clinical criteria for MCI were proposed by a group of investigators from the Mayo Clinic in the late 1990s 6. The criteria were derived from the clinical observation of signs and cognitive performance in patients in a longitudinal study of ageing and dementia in the community.

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      MCI was introduced as a clinical entity more than 20 years...

  4. onlinelibrary.wiley.com › doi › fullMild cognitive impairment as a diagnostic entity - Petersen ...

    Aug 20, 2004 · Recently, the construct of mild cognitive impairment (MCI) has been proposed to designate an early, but abnormal, state of cognitive impairment. MCI has generated a great deal of research from both clinical and research perspectives.

    • R. C. Petersen
    • 2004

  5. www.ncbi.nlm.nih.gov › pmc › articlesMild Cognitive Impairment: Ten Years Later - PMC

    Mild cognitive impairment represents the earliest clinical features of these conditions and, hence, has become a focus of clinical, epidemiological, neuroimaging, biomarker, neuropathological, disease mechanism and clinical trials research.

    • Ronald Carl Petersen, Rosebud O Roberts, David S Knopman, Bradley F Boeve, Yonas Endale Geda, Robert...
    • 10.1001/archneurol.2009.266
    • 2009
    • 2009/12

  6. pubmed.ncbi.nlm.nih.gov › 16549412Mild cognitive impairment (MCI) in medical practice: a ...

    Mild cognitive impairment (MCI) was proposed as a nosological entity referring to elderly people with mild cognitive deficit but no dementia. MCI is a heterogeneous clinical entity with multiple sources of heterogeneity.

  7. jamanetwork.com › journals › jamaneurologyMild Cognitive Impairment : Ten Years Later - JAMA Network

    Mild cognitive impairment represents the earliest clinical features of these conditions and, hence, has become a focus of clinical, epidemiologic, neuroimaging, biomarker, neuropathological, disease mechanism, and clinical trials research.

    • Ronald Carl Petersen, Rosebud O Roberts, David S Knopman, Bradley F Boeve, Yonas Endale Geda, Robert...
    • 2009
    • When did MCI become a clinical entity?1
    • When did MCI become a clinical entity?2
    • When did MCI become a clinical entity?3
    • When did MCI become a clinical entity?4

  8. www.sciencedirect.com › science › articleMild cognitive impairment and cognitive impairment, no ...

    Oct 1, 2007 · MCI as a clinical entity continues to be debated. Morris et al [46] , [96] argue that there is no such independent entity as MCI, simply AD at various levels of severity, with some individuals who have AD not even meeting criteria for dementia.

  9. psycnet.apa.org › record › 2006/12131/002For debate: Is mild cognitive impairment a clinically useful ...

    Mild cognitive impairment (MCI) has become a major issue in the fields of geriatrics, behavioral neurology and geriatric psychiatry. We pursued the concept of MCI because it offered insights into the earliest stages of dementing illness.

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