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Dec 2, 2015 · Time-kill test is the most appropriate method for determining the bactericidal or fungicidal effect. It is a strong tool for obtaining information about the dynamic interaction between the antimicrobial agent and the microbial strain.
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In recent years, there has been a growing interest in...
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Anaissie E, Paetznick V, Bodey GP. Fluconazole...
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What is the time-kill test? The time-kill test is a method used to evaluate the antimicrobial activity of a test material by measuring the reduction in the number of viable microorganisms over a specified period.
The Time-kill kinetics assay is used to study the activity of an antimicrobial agent against a bacterial strain and can determine the bactericidal or bacteriostatic activity of an agent over time.
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Time-Dependent Killing: For certain classes of antibiotics, the major killing effect against an organism is produced by either the time or the concentration of the drug at the binding site.
The Time Kill Test, or Time Kill Analysis, is carried out to evaluate an antimicrobial test material and assesses the in vitro reduction of a microbial population of test organisms after exposure to a test material.
Sep 17, 2016 · Time-kill curves that monitor bacterial growth and death over a wide range of antimicrobial concentrations have been frequently used to evaluate the effect of antimicrobials over time. These data can be analysed using mathematical models and are often the first step in PK/PD modelling.
