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Nabilone
- The earliest synthetic cannabinoid developed was Nabilone, a synthetic version of THC, back in the 1970s by Lilly Research.
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PB-22 and 5F-PB-22 were the first synthetic cannabinoids to include a quinoline substructure and an ester linkage. These compounds are thought to have been synthesized with the intention of making a synthetic cannabinoid prodrug, which might improve absorption and confound detection.
- Risks of Taking Synthetic Cannabinoids
- Withdrawal Effects
- Reducing The Risks
- Mental Wellbeing
- Smoking Synthetic Cannabinoids
- Support
Many people experience unpleasant and unpredictable effects and health risks after taking synthetic cannabinoids. This includes: 1. inability to move 2. dizziness 3. breathing difficulties 4. chest pain 5. heart palpitations 6. seizures 7. extreme anxiety 8. paranoia 9. suicidal thoughts 10. psychosis 11. gastrointestinal issues – like vomiting or ...
People who use synthetic cannabinoids regularly over a long time commonly have withdrawal symptoms. Symptoms reported include: 1. headaches 2. anxiety 3. low mood 4. difficulty concentrating 5. irritability 6. restlessness 7. cravings
Due to their potency, there’s no safe way to take synthetic cannabinoids. If someone does take them they should start low and go slow. Strength can be hugely variable so start with a very small dose – a match-head size or less. If using more, increase doses very cautiously and give time (at least an hour) for previous doses to wear off.
Synthetic cannabinoids may increase feelings of anxiety or paranoia. So, only use them in an environment in which you feel safe and with people you trust. Avoid using synthetic cannabinoids if you’re prone to anxiety or have existing mental health conditions.
Inhaling any substance into your lungs is going to cause some level of irritation to the delicate tissue. This includes synthetic cannabinoid products. If you’re smoking synthetic cannabinoids, avoid smoking them neat. Dried herbs can be used as an alternative to tobacco. Avoid holding smoke in your lungs or breathing in too deeply – take short puf...
If you would like help or support related to drug use please visit support for people affected by drugs.
Feb 6, 2023 · By 1964, Mechoulam and his colleagues had determined, for the first time, the full structure of both delta-9-tetrahydrocannabinol, better known to the world as THC (responsible for marijuana’s...
Nov 27, 2018 · The first scientists to study cannabis and create synthetic cannabinoids back in the 1940s had no idea that cannabinoid receptors even existed, nor did they know how marijuana’s phytochemicals interacted with other molecules in the body.
Dec 12, 2022 · Molecular structure of the first synthetic cannabinoid notified to the European Monitoring Centre for Drugs and Drug Addiction: JWH-018. The general structure of synthetic cannabinoid compounds can be described in four building blocks: core in blue, tail in green, linker in orange, and linked group in red [Colour figure can be viewed at ...
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- 15, Issue4
- 12 December 2022
The first synthetic cannabinoids found in these products are known as the JWH series, which were the most extensively studied in laboratory research. As laws banning the JWH compounds took effect, newer and less researched synthetic cannabinoids such as XR-11, AB-PINACA, and AB- FUBINACA were used in products since they had not been banned.
Jan 4, 2019 · Over the past 10 years, a group of drugs called synthetic cannabinoids, also known as Spice, K2 or synthetic marijuana, have been responsible for mass overdoses and tens of thousands of...
