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Buccal administration involves placing a drug between your gums and cheek, where it also dissolves and is absorbed into your blood. Both sublingual and buccal drugs come in tablets, films, or sprays.
Jul 18, 2024 · The main characteristic of buccal and sublingual routes of administration is the rapid onset of action (several minutes), which is due to the high blood flow and lymphatic flow of the oral cavity. In addition, substances absorbed at this level reach the general circulation without loss due to a first-pass effect, as the buccal venous drainage flows directly into the superior vena cava.
The oral mucosa has a thin epithelium and rich vascularity, which favor absorption; however, contact is usually too brief for substantial absorption. A drug placed between the gums and cheek (buccal administration) or under the tongue (sublingual administration) is retained longer, enhancing absorption.
Aug 23, 2023 · A sublingual or buccal route is another form of the enteral route of medication administration that offers the benefit of bypassing the first-pass effect. By applying the drug directly under the tongue (sublingual) or on the cheek (buccal), the medication undergoes a passive diffusion through the venous blood in the oral cavity, which bypasses the hepatic portal vein and flows into the ...
- Jean Kim, Orlando De Jesus
- 2023/08/23
- 2021
- Oral route. Many drugs can be administered orally as liquids, capsules, tablets, or chewable tablets. Because the oral route is the most convenient and usually the safest and least expensive, it is the one most often used.
- Injection routes. Administration by injection (parenteral administration) includes the following routes: Subcutaneous (under the skin) Intramuscular (in a muscle)
- Sublingual and buccal routes. A few drugs are placed under the tongue (taken sublingually) or between the gums and teeth (buccally) so that they can dissolve and be absorbed directly into the small blood vessels that lie beneath the tongue.
- Rectal route. Many drugs that are administered orally can also be administered rectally as a suppository. In this form, a drug is mixed with a waxy substance that dissolves or liquefies after it is inserted into the rectum.
Sublingual and buccal medications are administered by placing them in the mouth, either under the tongue (sublingual) or between the gum and the cheek (buccal). The medications dissolve rapidly and are absorbed through the mucous membranes of the mouth, where they enter into the bloodstream. The medications are compounded in the form of small ...
People also ask
What is the difference between Buccal administration and sublingual administration?
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What is Buccal administration?
Lozenge—effects a metred and patient-controlled-rate combination of sublingual, buccal, and oral administration, as with the Actiq fentanyl. Effervescent buccal or sublingual tablets—this method drives the drug through the mucous membranes much faster (this is the case in the stomach with carbonated or effervescent liquids as well) and is used in the Fentora fentanyl buccal tablet.
