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  2. Hereditary spastic paraplegia is a general term for a group of rare inherited disorders that cause weakness and stiffness in the leg muscles. Symptoms gradually get worse over time. It's also known as familial spastic paraparesis or Strümpell-Lorrain syndrome.

    • Overview
    • Possible Causes
    • Care and Treatment
    • When to Call the Doctor

    Spasticity is a symptom and characteristic of certain neurological conditions. It causes certain muscles to contract all at once. It ranges in severity and can affect movement and speech. There are several treatment options for spasticity, including physical therapy, medication and botulinum toxin injections.

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    OverviewPossible CausesCare and TreatmentWhen to Call the Doctor

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    What causes spasticity?

    Spasticity is usually caused by damage to nerve pathways within your brain or spinal cord that control movement and stretch reflexes. Spasticity may occur due to several conditions, including: Spinal cord injury. Multiple sclerosis (MS). Cerebral palsy. Stroke. Brain or head injury. Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. Hereditary spastic paraplegias. Adrenoleukodystrophy (ALD). Phenylketonuria. Krabbe disease.

    How is spasticity treated?

    There are several treatment options for spasticity. People who have spasticity usually undergo more than one treatment at a time. Though there’s no cure for spasticity, these treatments can help alleviate symptoms and improve quality of life. The most effective way to treat spasticity is with a team of healthcare professionals with different specialties. Members of this team may include one or more of the following: Neurologist. Physiatrist (a rehabilitation specialist). Advanced practice clinician. Physical therapist. Occupational therapist. Speech and language pathologist. Neurosurgeon. Orthopaedic surgeon.

    When should I see my healthcare provider about spasticity?

    It’s important to seek medical care if you experience spasticity for the first time with no known cause, since spasticity may be a sign of damage to your brain or spinal cord. If you’ve been diagnosed with spasticity, see your healthcare provider if the spasticity is worsening and/or becoming more frequent or if it’s interfering with everyday tasks. A note from Cleveland Clinic Spasticity is a common symptom and feature of several neurological conditions. The severity of spasticity can range from a minor inconvenience to a significant disruption of your day-to-day life. The good news is that there are several treatment options for spasticity. Together, you’ll work with your healthcare team to determine the best treatment plan for you. Medically Reviewed Last reviewed by a Cleveland Clinic medical professional on 07/23/2022. Learn more about our editorial process.

  3. Jan 17, 2020 · Spastic paresis is a condition that causes muscle overactivity and spasticity. It’s due to nerve damage that often results from conditions like stroke, MS, and cerebral palsy.

  4. Aug 22, 2024 · Hereditary spastic paraplegia (pronounced “huh-RED-eh-ter-ee” “SPAS-ti”k “par-uh-PLEE-jee-uh”) is a group of inherited conditions that cause weakness and tightness (spasticity) in your leg muscles. Symptoms are progressive. This means they get worse over time.

  5. Jul 12, 2017 · The hereditary spastic paraplegias (HSP) are a large group of inherited neurologic disorders that share the primary symptom of difficulty walking due to muscle weakness and muscle tightness (spasticity) in the legs.

  6. Jul 19, 2024 · Hereditary spastic paraplegia (HSP), also known as familial spastic paraparesis, refers to a group of inherited disorders that involves weakness and spasticity, which is stiffness of the legs. These symptoms get worse over time. Early in the disease, there may be mild trouble walking and stiffness.

  7. Hereditary spastic paraplegia (HSP) is a group of inherited diseases whose main feature is a progressive gait disorder. The disease presents with progressive stiffness (spasticity) and contraction in the lower limbs. [1] .

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