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What are lipid emulsions?
What is intravenous lipid emulsion therapy?
What is a balanced lipid emulsion?
When should lipid emulsions be used?
Lipid emulsion or fat emulsion refers to an emulsion of fat for human intravenous use, to administer nutrients to critically-ill patients that cannot consume food. It is often referred to by the brand name of the most commonly used version, Intralipid, which is an emulsion containing soybean oil, egg phospholipids and glycerin, and is available ...
Feb 16, 2024 · Intravenous lipid emulsion (ILE) therapy, also known as lipid resuscitation therapy, is the established standard treatment for local anesthetic systemic toxicity (LAST), including local anesthetic-mediated cardiac arrest.
- Ernesto A. Sepulveda, Aimee Pak
- 2024/02/16
- 2019
Lipid emulsion creates an expanded intravascular lipid phase that causes lipophilic agents to be extracted from the target tissue and bind to the lipid, thereby reversing toxicity. 71 Because many OP compounds are highly lipid soluble and formulated in lipid solvents, lipid emulsion has been suggested as a treatment modality for OP poisoning.
Jul 14, 2024 · Intralipid and lipid rescue therapy as an antidote of last resort in cardiotoxic overdoses of lipophilic agents (best described for bupivacaine)
This review will focus on the clinical application of lipid emulsion therapy in resuscitation from drug-related toxicity and will provide an introduction to the development of the method, guidelines for its use, and insights into potential controversies and future applications.
- Guy L. Weinberg
- 2012
Apr 29, 2020 · Lipid emulsions (LEs), an integral component in parenteral nutrition (PN) feeding, have shifted from the primary aim of delivering non-protein calories and essential fatty acids to defined therapeutic outcomes such as reducing inflammation, and improving metabolic and clinical outcomes.
Nov 18, 2009 · A lipid emulsion should usually be provided with PN to prevent depletion of essential fatty acids, lower the risk of hyperglycaemia, and prevent hepatic steatosis. If PN is indicated, lipid emulsions should commence after hemodynamic stability has been established or achieved.