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  2. Jan 4, 2024 · Spindle fibres (protein microtubules) begin to shorten. The separated sister chromatids (now called chromosomes) are pulled to opposite poles by the spindle fibres (protein microtubules)

  3. It is referred to as the mitotic spindle during mitosis, a process that produces genetically identical daughter cells, or the meiotic spindle during meiosis, a process that produces gametes with half the number of chromosomes of the parent cell.

    • Regina Bailey
    • Interphase. Before a dividing cell enters mitosis, it undergoes a period of growth called interphase. About 90 percent of a cell's time in the normal cell cycle may be spent in interphase.
    • Prophase. In prophase, the chromatin condenses into discrete chromosomes. The nuclear envelope breaks down and spindles form at opposite poles of the cell.
    • Metaphase. In metaphase, the spindle reaches maturity and the chromosomes align at the metaphase plate (a plane that is equally distant from the two spindle poles).
    • Anaphase. In anaphase, the paired chromosomes (sister chromatids) separate and begin moving to opposite ends (poles) of the cell. Spindle fibers not connected to chromatids lengthen and elongate the cell.
  4. Today, mitosis is understood to involve five phases, based on the physical state of the chromosomes and spindle. These phases are prophase, prometaphase, metaphase, anaphase, and telophase.

  5. The mitotic spindle is a microtubule-based structure that controls the proper segregation of chromosomes during mitosis [1]. Within the mitotic spindle, microtubules coordinate the congression of chromosomes to the metaphase plate before their ultimate segregation during anaphase.

  6. The spindle fibres line sister chromatid pairs up in the centre of the cell. This location is known as the. equator. . Stage four. The spindle fibres contract and separate the sister...

  7. These tubules, collectively known as the spindle, extend from structures called centrosomes — with one centrosome located at each of the opposite ends, or poles, of a cell. As mitosis progresses...

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