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- Host–guest interactions involve two molecules or materials that can form complexes through unique structural relationships and noncovalent binding. Also referred to as molecular recognition, this type of interaction is widely found in biorecognition processes, such as enzyme–inhibitor and antigen–antibody interactions.
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How do host-guest interactions regulate the working of proteins?
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Nov 23, 2009 · For example, the molecular recognition of cholesterol by cyclodextrin is described as the formation of “host-guest complex” by an organic chemist while the molecular recognition of cholesterol by the enzyme cholesterol oxidase would be used as an example of “substrate binding” by a biochemist.
Jan 4, 2021 · Host–guest interactions regulate the working of proteins and have been intensively studied 1, 2. Atomistic simulations have been widely used 3, 4, 5, 6, 7 to calculate key parameters like...
- Valerio Rizzi, Valerio Rizzi, Luigi Bonati, Luigi Bonati, Narjes Ansari, Narjes Ansari, Michele Parr...
- 2021
Host–guest chemistry encompasses the idea of molecular recognition and interactions through non-covalent bonding. Non-covalent bonding is critical in maintaining the 3D structure of large molecules, such as proteins and is involved in many biological processes in which large molecules bind specifically but transiently to one another.
It is the fact that molecular hosts bind more tightly to certain “guest” molecules than others. What is the physical basis for it? There are two possible sources for this — covalent, where certain guests have the...
- P. A. Kollman
- 1994
Mar 2, 2021 · The review uses informative examples of aqueous host–guest chemistry organized around generalizable themes and lessons, building towards lessons focused on molecular recognition in salty solutions and biological fluids.
- Meagan A. Beatty, Fraser Hof
- 2021
Jan 18, 2021 · Host-guest recognition between p-sulfocalix arene and toluidine blue is chosen to ensure reliable and clear electrical signal . Labeled signal probe and auxiliary probe are also used to bind with Au@SCX8-RGO-toluidine blue nanocomposites.
Sep 14, 2018 · Biosensors are powerful diagnostic tools defined as having a biorecognition element for analyte specificity and a transducer for a quantifiable signal. There are a variety of different biorecognition elements, each with unique characteristics.
