Conjugates for fixed-cell staining. Select reagents for endoplasmic reticulum. CellLight reagents For ER. ER-tracker dyes for live cells. See selection guide.
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Primary antibodies for organelles
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Oct 18, 2024 · endoplasmic reticulum (ER), in biology, a continuous membrane system that forms a series of flattened sacs within the cytoplasm of eukaryotic cells and serves multiple functions, being important particularly in the synthesis, folding, modification, and transport of proteins . All eukaryotic cells contain an endoplasmic reticulum (ER).
- Smooth Endoplasmic Reticulum
Smooth endoplasmic reticulum, meshwork of fine tubular...
- Sarcoplasmic Reticulum
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- Rough Endoplasmic Reticulum
Rough endoplasmic reticulum, series of connected flattened...
- Smooth Endoplasmic Reticulum
Jul 1, 2024 · The endoplasmic reticulum (ER) is the largest membrane-bound organelle that regulates essential cellular processes, including secreted and membrane protein folding, calcium storage and lipid synthesis (Karagöz et al., 2019, Radanović and Ernst, 2021). The vast structural and compositional diversity of the ER enables it to perform these diverse functions.
- Endoplasmic Reticulum Definition
- Endoplasmic Reticulum Overview
- Endoplasmic Reticulum Function
- Structure of The Endoplasmic Reticulum
- Endoplasmic Reticulum Location
- Types of Endoplasmic Reticulum
The endoplasmic reticulum (ER) is a large organelle made of membranous sheets and tubules that begin near the nucleus and extend across the cell. The endoplasmic reticulum creates, packages, and secretes many of the products created by a cell. Ribosomes, which create proteins, line a portion of the endoplasmic reticulum.
The entire structure can account for a large proportion of the endomembrane system of the cell. For instance, in cells such as liver hepatocytes that are specialized for protein secretion and detoxification, the ER can account for more than 50% of the total lipid bilayer of the cell.Similarly, the ER membrane system is particularly prominent in pan...
The ER plays a number of roles within the cell, from protein synthesis and lipid metabolism to detoxification of the cell. Cisternae, each of the small folds of the endoplasmic reticulum, are commonly associated with lipid metabolism. This creates the plasma membrane of the cell, as well as additional endoplasmic reticulum and organelles. They also...
The endoplasmic reticulum membrane system can be morphologically divided into two structures–cisternae and sheets. Cisternae are tubular in structure and form a three-dimensional polygonal network.They are about 50 nm in diameter in mammals and 30 nm in diameter in yeast. ER sheets, on the other hand, are membrane-enclosed, two-dimensional flattene...
The endoplasmic reticulum processes most of the instructions from the nucleus. As such, the endoplasmic reticulum surrounds the nucleus and radiates outward. In cells that secrete many products for the rest of the body, the endoplasmic reticulum can account for more than 50% of the cell. In general, the nucleus expresses mRNA (messenger RNA), which...
There are two major types of ER within each cell – smooth endoplasmic reticulum (SER) and rough endoplasmic reticulum (RER). Each has distinct functions, and often, differing morphology. The SER is involved in lipid metabolism and acts as the calcium store for the cell. This is particularly important in muscle cells that need Ca2+ions for contracti...
- Gabe Buckley
However, the morphological features of the endoplasmic reticulum (ER) in hPSCs and consequent susceptibility of stem cells have not been reported. The ER is an organelle found in all eukaryotic cells that extends from the nuclear membrane to form a network of tubules, vesicles, and cisterna, with an overall structure resembling that of the cell membrane [ 8 ].
Sep 7, 2021 · The endoplasmic reticulum (ER) is an organelle that is responsible for many essential subcellular processes. Interconnected narrow tubules at the periphery and thicker sheet-like regions in the perinuclear region are linked to the nuclear envelope. It is becoming apparent that the complex morphology and dynamics of the ER are linked to its ...
- Hannah T. Perkins, Viki Allan
- 10.3390/cells10092341
- 2021
- Cells. 2021 Sep; 10(9): 2341.
Oct 31, 2023 · The Endoplasmic Reticulum. The endoplasmic reticulum (ER) is a series of interconnected membranous sacs and tubules that collectively modifies proteins and synthesizes lipids. However, these two functions are performed in separate areas of the ER: the rough ER and the smooth ER. The hollow portion of the ER tubules is called the lumen or ...
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The rough endoplasmic reticulum (RER) is so named because the ribosomes attached to its cytoplasmic surface give it a studded appearance when viewed through an electron microscope (Figure 5.9.2 5.9. 2). The ribosomes synthesize proteins while attached to the ER, resulting in transfer of their newly synthesized proteins into the lumen of the RER ...
