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      • Allison’s breakthrough was the discovery of a sort of secret handshake that cancer uses to evade the immune system, and a means to block that handshake—what the Nobel committee hailed as “a landmark in our fight against cancer,” which has “revolutionized cancer treatment, fundamentally changing the way we view how cancer can be managed.” (Allison’s co-recipient was Tasuku Honjo of Kyoto University.)
      www.wired.com/story/meet-jim-allison-the-texan-who-just-won-a-nobel-cancer-breakthrough/
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  2. The story of one warmhearted, stubborn man’s visionary quest to find a cure for cancer, Jim Allison: Breakthrough is an homage to an unconventional superhero — a pioneering, harmonica-playing...

  3. Jim Allison: Breakthrough: Directed by Bill Haney. With Jim Allison, Sharon Belvin, Eric Benson, Woody Harrelson. Renegade Texan scientist Jim Allison devotes his life work to find a cure for cancer after the disease takes the life of his mother.

    • (233)
    • Documentary
    • Bill Haney
    • 2019-09-27
    • Taking The Brake Off T Cells
    • The Power of Curiosity
    • Allison’s Start in Science
    • First Stop: Smithville
    • There’S Still Work to Be Done

    The Nobel Prize recognizes Allison’s breakthrough work with T cells, the “soldiers” of the immune system that battle invaders and abnormal cells like cancer, bacteria and viruses. While T cells are fierce opponents of disease, they don’t attack every invader that comes along. If they did, the body would be in a constant state of fever, rash, inflam...

    “I never dreamed my research would take the direction it has,” says Allison, whose mother died of lymphomawas he was just 10. “It’s a great, emotional privilege to meet cancer patients who’ve been successfully treated with immune checkpoint blockade. They are living proof of the power of basic science, of following our urge to learn and to understa...

    The son of a country doctor, Allison grew up in Alice, Texas, seemingly destined for medical school. A lifelong interest in understanding how things work, and observing his father practicing medicine day-in and day-out, led to a decisive conclusion. “I had a pretty good look at what it’s like to be a physician. As a doctor, you can’t make mistakes,...

    Allison started his career at MD Anderson in 1977, arriving as one of the first employees of the institution’s Science Park, a new basic science research center located in Smithville, Texas, where he made his first major discoveries. He was recruited back to MD Anderson in 2012 to lead the Immunology Department and to establish an immunotherapy res...

    Under his leadership, with Scientific Director Padmanee Sharma, M.D., Ph.D., the immunotherapy platform conducts immune monitoring by analyzing tumor samples before, during and after treatment, in order to understand why these drugs work for some patients but not all. The platform works with more than 100 immunotherapy clinical trialsat MD Anderson...

  4. Mar 15, 2021 · Jim Allison: Breakthrough is the astounding, true story of one warm-hearted, stubborn man’s visionary quest to find a cure for cancer. Today, Jim Allison is a name to be reckoned with throughout the scientific world — a 2018 Nobel Prize winner for discovering the immune system’s role in defeating cancer but for decades he waged a lonely ...

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  5. Dec 16, 2019 · But the new docu­mentary Jim Allison: Breakthrough does a pretty amazing job. It chronicles the pioneering researcher whose work helped create checkpoint inhibitor immunotherapy, which unleashes the immune system against cancer, and won him a Nobel prize, shared with Tasuku Honjo, MD, PhD, in 2018.

  6. Jim Allison: Breakthrough is the astounding, true story of one warmhearted, stubborn man’s visionary quest to find a cure for cancer. Today, Jim Allison is a name to be reckoned with throughout the scientific world — a 2018 Nobel Prize winner for discovering the immune system’s role in defeating cancer — but for decades he waged a ...

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