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- DictionaryHashimoto's disease/ˌhaʃɪˈməʊtəʊz/
noun
- 1. an autoimmune disease causing chronic inflammation and consequential failure of the thyroid gland.
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Apr 22, 2021 · The thing to understand about Hashimoto’s disease is that it is basically a variant of hypothyroidism, caused specifically by autoimmunity; the thyroid gets infiltrated by white cells and slowly loses its function; it usually enlarges but may not, and may start with an over-active phase before becoming under-active.
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Hashimoto's disease progresses slowly over the years. You may not notice signs or symptoms of the disease. Eventually, the decline in thyroid hormone production can result in any of the following:
•Fatigue and sluggishness
•Increased sensitivity to cold
•Increased sleepiness
•Dry skin
•Constipation
Signs and symptoms of Hashimoto's disease vary widely and are not specific to the disorder. Because these symptoms could result from any number of disorders, it's important to see your health care provider as soon as possible for a timely and accurate diagnosis.
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Hashimoto's disease is an autoimmune disorder. The immune system creates antibodies that attack thyroid cells as if they were bacteria, viruses or some other foreign body. The immune system wrongly enlists disease-fighting agents that damage cells and lead to cell death.
What causes the immune system to attack thyroid cells is not clear. The onset of disease may be related to:
•Genetic factors
•Environmental triggers, such as infection, stress or radiation exposure
The following factors are associated with an increased risk of Hashimoto's disease:
•Sex. Women are much more likely to get Hashimoto's disease.
•Age. Hashimoto's disease can occur at any age but more commonly occurs during middle age.
•Other autoimmune disease. Having another autoimmune disease — such as rheumatoid arthritis, type 1 diabetes or lupus — increases your risk of developing Hashimoto's disease.
•Genetics and family history. You're at higher risk for Hashimoto's disease if others in your family have thyroid disorders or other autoimmune diseases.
•Pregnancy. Typical changes in immune function during pregnancy may be a factor in Hashimoto's disease that begins after pregnancy.
Thyroid hormones are essential for the healthy function of many body systems. Therefore, when Hashimoto's disease and hypothyroidism are left untreated, many complications can occur. These include:
•Goiter. A goiter is enlargement of the thyroid. As thyroid hormone production declines due to Hashimoto's disease, the thyroid receives signals from the pituitary gland to make more. This cycle may result in a goiter. It's generally not uncomfortable, but a large goiter can affect your appearance and may interfere with swallowing or breathing.
•Heart problems. Hypothyroidism can result in poor heart function, an enlarged heart and irregular heartbeats. It can also result in high levels of low-density lipoprotein (LDL) cholesterol — the "bad" cholesterol — that is a risk factor for cardiovascular disease and heart failure.
•Mental health issues. Depression or other mental health disorders may occur early in Hashimoto's disease and may become more severe over time.
•Sexual and reproductive dysfunction. In women, hypothyroidism can result in a reduced sexual desire (libido), an inability to ovulate, and irregular and excessive menstrual bleeding. Men with hypothyroidism may have a reduced libido, erectile dysfunction and a lowered sperm count.
•Poor pregnancy outcomes. Hypothyroidism during pregnancy may increase the risk of a miscarriage or preterm birth. Babies born to women with untreated hypothyroidism are at risk for decreased intellectual abilities, autism, speech delays and other developmental disorders.
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A condition called Hashimoto's disease is the most common type of autoimmune reaction that causes an underactive thyroid. It's not clear what causes Hashimoto's disease, but it runs in families. It's also common in people with another immune system disorder, such as type 1 diabetes and vitiligo.
Jun 26, 2023 · What is Hashimoto’s disease? Hashimoto’s disease is an autoimmune condition that can cause hypothyroidism (underactive thyroid). It’s a lifelong (chronic) condition. Your thyroid is a small, butterfly-shaped gland located at the front of your neck under your skin.
May 9, 2023 · Hashimoto's disease (HD), also called Hashimoto's autoimmune thyroiditis, is an autoimmune disease that damages and enlargens the thyroid gland. The damage lowers the level of hormones it can produce, leading to hypothyroidism (low thyroid activity).
- Adrienne Dellwo
What is Hashimoto’s disease? Hashimoto’s disease is an autoimmune disorder that can cause hypothyroidism, or underactive thyroid. Rarely, the disease can cause hyperthyroidism, or overactive thyroid. The thyroid is a small, butterfly-shaped gland in the front of your neck. In people with Hashimoto’s disease
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Oct 26, 2023 · Also called Hashimoto's disease, Hashimoto's thyroiditis is an autoimmune disease, a disorder in which the body's immune system attacks healthy or normal cells. In people...
