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Epstein-Barr virus (EBV) infection
- The Monospot test detects heterophile antibodies produced by the immune system in response to Epstein-Barr virus (EBV) infection.
labtestsonline.org.uk/tests/monospot-test
People also ask
What causes antibodies to be detected by monospot?
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Can a monospot test detect Epstein-Barr virus (EBV) infection?
What does a positive monospot test mean?
What is the sensitivity of a monospot test?
What is a mononuclear spot test?
Aug 14, 2023 · The monospot test is a latex agglutination test which utilizes equine erythrocytes as the primary substrate and tests for specific heterophile antibodies produced by the human immune system in response to EBV infection.
- Nathan D. Stuempfig, Justin Seroy
- 2023/08/14
The antibodies detected by monospot can be caused by conditions other than glandular fever. The monospot produces both false-positive and false-negative results. For example, the heterophile antibodies detected by monospot are often not present in children with glandular fever.
Nov 16, 2021 · The Monospot test detects heterophile antibodies produced by the immune system in response to Epstein-Barr virus (EBV) infection. These antibodies can cross-react with other types of cells, including horse red blood cells (the ones used in the monospot).
Sep 11, 2024 · Monospot test. Primary EBV infection of B lymphocytes results in the release of heterophile antibodies, which react with animal antigens including horses. The monospot test exposes a patient’s blood sample to a solution rich in equine erythrocytes.
The monospot test is used to diagnose glandular fever (infectious mononucleosis) by detecting the antibodies your body makes to the Epstein-Barr virus (EBV) which causes the infection. It is used as an initial screen because only 70 to 80 percent of cases of glandular fever produce antibodies.
The mononuclear spot test or monospot test, a form of the heterophile antibody test, [1] is a rapid test for infectious mononucleosis due to Epstein–Barr virus (EBV). It is an improvement on the Paul–Bunnell test. [2] The test is specific for heterophile antibodies produced by the human immune system in response to EBV
Sep 4, 2023 · The monospot test is primarily used to detect the presence of heterophile antibodies in the blood. These antibodies are produced in response to the Epstein-Barr virus (EBV), which is the most common cause of mono.
