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  1. Jul 22, 2024 · WHO's new guidelines prioritize broader access to PEP, including community-based delivery and task sharing to mitigate barriers such as stigma and to ensure timely access post-exposure. PEP involves the administration of antiretroviral medications to individuals at risk of HIV infection after potential exposure.

  2. Sep 22, 2023 · WHO has made available the membership of the Guidelines Development Group (GDG) for the update of their Guidelines for HIV post-exposure prophylaxis (PEP) (2023). This proposed update to the existing PEP guidelines will include new recommendations about how best to expand access to PEP.

  3. Jul 22, 2024 · PEP is most effective when initiated as soon as possible, ideally within 24 hours and no later than 72 hours after exposure. While a PEP regimen of two drugs can be effective, three drugs are preferred. It is recommended that people be given a 28-day prescription for PEP. This guideline includes recommended drug regimens for adults, adolescents ...

  4. New in the 2021 guideline 1. The indications for, and management of, PEP following occupational exposures, specifically sharps (percutaneous) injuries, splash (mucocutaneous) injuries and bites is covered in this guideline. 2. Inclusion of indications for PEP following injecting drug use, including sexualized drug use. 3.

  5. Nov 9, 2023 · Post-exposure prophylaxis (PEP) to prevent HIV acquisition has been recommended for over three decades, but remains underutilised. Over the past decade, clinical trials have established the safety and tolerability of newer PEP regimens, particularly those containing integrase strand transfer inhibitors (INSTIs) combined with a tenofovir and lamivudine or emtricitabine backbone. Several of ...

  6. This serves as an update to the 2015 BASHH guideline on PEP following sexual exposures and the 2008 Expert Advisory Group on AIDS guidelines on HIV PEP. We aim to provide evidence-based guidance on best clinical practice in the provision, monitoring and support of PEP for the prevention of HIV acquisition following sexual, occupational and other non-occupational exposures in the community.

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  8. PEP is most effective when initiated as soon as possible, ideally within 24 hours and no later than 72 hours after exposure. While a PEP regimen of two drugs can be effective, three drugs are preferred. It is recommended that people be given a 28-day prescription for PEP. This guideline includes recommended drug regimens for adults, adolescents ...

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