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1. www.angus.gov.uk › media › p19_significant_caseP19 Significant case review report (PDF) - Angus Council

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   P19 Significant case review report.pdf 984.33 KB Alternative formats If you require this document in a more accessible, alternative format request it using our accessibility feedback form .

2. People also ask

   What is a P19 cell?

   • P19 cells is an embryonic carcinoma cell line derived from an embryo-derived teratocarcinoma in mice. The cell line is pluripotent and can differentiate into cell types of all three germ layers.

   P19 cell - Wikipedia

   en.wikipedia.org/wiki/P19_cell

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   What are embryonal carcinoma P19 cells?

   • These stem cells were named embryonal carcinoma P19 cells. [ 2] These derived P19 cells grew rapidly without feeder cells and were easy to maintain. Moreover, the multipotency of P19 cells was then confirmed by injecting the cells into blastocysts of another mouse strain.

   P19 cell - Wikipedia

   en.wikipedia.org/wiki/P19_cell

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   Are p19 EC cells multipotent?

   • P19 EC cells, isolated from an experimental embryo-derived teratocarcinoma in mice, are multipotent and can differentiate into cell types of all three germ layers.

   Twenty one years of P19 cells: what an embryonal carcinoma cell line

   academic.oup.com/cardiovascres/article/58/2/292/340911

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   Are p19 EC cells stem cells?

   • The stem cell nature of the P19 EC cells was subsequently verified by injection into blastocysts of a different strain. P19 EC derived cells were found in tissues of all three germ layers in the resulting chimaeric mice, even when only a single P19 EC cell was injected .

   Twenty one years of P19 cells: what an embryonal carcinoma cell line

   academic.oup.com/cardiovascres/article/58/2/292/340911

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   Why is p19 important?

   • Because P19 suppresses RNAi in diverse systems, its structure is known, specific siRNA-binding mutants are available and the protein is easily expressed and purified to high amounts, it is predictable that P19 will become increasingly valuable as a tool to dissect the RNAi pathway in various organisms and in vitro.

   The Tombusvirus-encoded P19: from irrelevance to elegance | Nature

   www.nature.com/articles/nrmicro1395

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   How does p19Arf work?

   • p19ARF acts through both the p53 and the Rb pathways. The availability of cell lines that are reversibly dependent upon the absence of p16 INK4A or p19 ARF function allowed us to test whether inactivation of each gene was functionally equivalent.

   p16INK4A and p19ARF act in overlapping pathways in cellular ... - Nature

   www.nature.com/articles/ncb0300_148

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3. en.wikipedia.org › wiki › P19_cellP19 cell - Wikipedia

   en.wikipedia.org › wiki › P19_cell

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   P19 cell is a pluripotent cell line derived from a mouse teratocarcinoma that can differentiate into cells of all three germ layers. It is widely used to study the mechanisms of drug-induced differentiation, especially neurogenesis and myogenesis, and the related signaling pathways.

4. nph.onlinelibrary.wiley.com › doi › fullThe viral silencing suppressor P19 interacts with the ...

   nph.onlinelibrary.wiley.com › doi › full

   Oct 2, 2020 · P19 binds sRNA duplexes and inhibits RNA silencing in a cell-autonomous manner (Silhavy et al., 2002; Vargason et al., 2003; Ye et al., 2003); notably, P19 also suppresses the intercellular spread of silencing, and this property is assumed to be the direct result of sRNA sequestration by the viral protein, an idea supported by ...

   • Author: Borja Garnelo Gόmez, Tabata Rosas‐Díaz, Chaonan Shi, Pengfei Fan, Dan Zhang, Jose S. Rufián, Rosa Lo...
   • Cited By: 19

   • Publish Year: 2021
   • Published: 02 October 2020

5. academic.oup.com › cardiovascres › articleTwenty one years of P19 cells: what an embryonal carcinoma ...

   academic.oup.com › cardiovascres › article

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   May 1, 2003 · P19 cells are embryonal carcinoma cells derived from mouse teratocarcinomas that can differentiate into various cell types, including cardiomyocytes. This review summarizes the studies on P19 cells and their subclones that have contributed to our understanding of cardiac cell development and physiology.

   • Author: Marcel A.G. van der Heyden, Libert H.K. Defize

   • Publish Year: 2003

6. www.nature.com › articles › nrmicro1395The Tombusvirus -encoded P19: from irrelevance to elegance

   www.nature.com › articles › nrmicro1395

   Mar 6, 2006 · Since its discovery in the late 1980s, the status of the Tombusvirus -encoded p19 protein (P19) changed from being thought obsolete to its identification a decade later as an important viral...

   • Author: Herman B. Scholthof

   • Publish Year: 2006

7. www.culturecollections.org.uk › nop › productP19. Culture Collections

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   P19. Cell Line Description. The P19 cell line was derived from an embryonal carcinoma induced in a C3H/He strain mouse. The cells can be cloned at high efficiency in medium containing 0.1mM beta-mercaptoethanol. The pluripotent P19 cells can be induced to differentiate into neuronal and glial cells in the presence of retinoic acid.

8. www.nature.com › articles › ncb0300_148p16INK4A and p19ARF act in overlapping pathways in ... - Nature

   www.nature.com › articles › ncb0300_148

   Feb 8, 2000 · The INK4A locus encodes two independent but overlapping genes, p16INK4A and p19ARF, and is frequently inactivated in human cancers. The unusual structure of this locus has lead to ambiguity...