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Oct 27, 2023 · Last, we identified herb-symptom pairs that are predicted to be effective based on network proximity and proven effective in the patient data but not yet recognized by the TCM community, highlighting the translational value of our framework in prioritizing effective herb treatment against diseases, which can further lead to drug discovery and repurposing opportunities.
Oct 27, 2023 · Understanding natural and traditional medicine can lead to world-changing drug discoveries. Despite the therapeutic effectiveness of individual herbs, traditional Chinese medicine (TCM) lacks a scientific foundation and is often considered a myth. In this study, we establish a network medicine frame …
Oct 27, 2023 · apeutic effectiveness of individual herbs, traditional Chinese medicine (TCM) lacks a scientificfoundation and is often considered a myth. In this study, we establish a network medicine framework and reveal the general TCM treatment principle as the topological relationship between disease symptoms and TCM herb targets on the human protein ...
Traditional Chinese medicine (TCM) relies on natural medical products to treat symptoms and diseases. While clinical data have demonstrated the effectiveness of selected TCM-based treatments, the mechanistic root of how TCM herbs treat diseases remains largely unknown.
Our network medicine framework reveals the scientific foundation of TCM and establishes a paradigm for understanding the molecular basis of natural medicine and predicting disease treatments. AB - Understanding natural and traditional medicine can lead to world-changing drug discoveries.
- eadh0215
- English
- Science Advances
- eadh0215
Jul 18, 2022 · Traditional Chinese medicine (TCM) relies on natural medical products to treat symptoms and diseases. While clinical data have demonstrated the effectiveness of selected TCM-based treatments, the mechanistic root of how TCM herbs treat diseases remains largely unknown. More importantly, current approaches focus on single herbs or prescriptions, missing the high-level general principles of TCM ...
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Is TCM herbal treatment based on a network medicine framework?
Is TCM a topological relationship between disease symptoms and TCM herb targets?
How do TCM herbs treat diseases?
Are TCM herbal treatments effective?
What is a network medicine framework?
What is the translational value of the network medicine framework?
network-based framework captures symptom-disease relations and herb- ... general effectiveness of traditional Chinese medicine (TCM) herbs. In ... the team did not set out to test whether TCM ...