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      • The main component of milk thistle that bears active biological properties is silymarin. Silymarin is a composite of flavonolignans namely silybin A and B (SBN A&B) 50%, isosilybin A and B (ISBN A&B) 5%, silychristin (SCN) 20%, and silydianin 10%.
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  2. Dec 6, 2018 · How much milk thistle is safe to take? The European Medicines Agency recommends taking 300mg-600mg of milk thistle, two or three times a day. 8 These people should avoid taking milk thistle extract: 9,10

  3. The flavonolignan silibinin, the major bioactive component of the silymarin extract of Silybum marianum (milk thistle) seeds, is gaining traction as a novel anti-cancer therapeutic. Here, we review the historical developments that have laid the groundwork for the evaluation of silibinin as a chemopreventive and therapeutic agent in human lung ...

  4. Mar 1, 2022 · The main phytochemical extract of the milk thistle plant is silymarin. It has optimistic, protective, and therapeutic properties. However, evidence about the role of milk thistle extracts in oral diseases is lacking.

  5. Jul 22, 2024 · Silybin, or silibinin, is a polyphenolic flavonoid that naturally occurs in the plant known as milk thistle (Silybum marianum). It is the primary component of the milk thistle extract known as silymarine. Silybin is not only the major element (50 to 70%) of silymarin but also its most active ingredient.

  6. en.wikipedia.org › wiki › SilibininSilibinin - Wikipedia

    Silibinin itself is a mixture of two diastereomers, silybin A and silybin B, in approximately equimolar ratio. [1] Silibinin is used in pure forms as a medication, and more frequently as an active ingredient in milk thistle–derived herbal supplements.

  7. Sep 11, 2023 · What Is Milk Thistle Used For? People have traditionally used milk thistle for problems with the liver and gallbladder . Experts believe silymarin is the primary active ingredient of the...

  8. Early research shows that giving silibinin, a chemical found in milk thistle may lessen liver damage caused by Amanita phalloides mushroom (death cap mushroom) poisoning. However, it is hard to...

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