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  1. Jul 13, 2021 · 1-2 years. Vaginal atrophy. 3-6 months. 1-2 years. Deepened voice. 3-12 months. 1-2 years. The degree and rate of the HRT timeline on physical effects depends in part on the dose, route of administration, and medications used. These are selected in accordance with a patient’s specific medical goals. (e.g., changes in gender role expression ...

    • Effects of Estrogen Treatment
    • Methods For Taking Estrogen
    • Types of Estrogens
    • Risks and Benefits
    • Treatment and Gender Surgery

    Androgen blockers are a necessary part of estrogen treatment for transfeminine people because testosterone acts more strongly in the body than estrogen does. Therefore, in order for transfeminine people to experience the effects of estrogen treatment, they must block their testosterone. The most common medication used to block testosterone is spiro...

    When used for gender-affirming care, estrogen is available in different formulations: 1. Oral pill (taken by mouth and swallowed) 2. Sublingual tablet (dissolved under the tongue) 3. Intramuscular injection (injected into a large muscle) 4. Subcutaneous injection (injected under the skin) 5. Transdermal patch (delivered through the skin in an adhes...

    In addition to the different routes of administration of estrogen treatment, there are also different types of estrogens used for treatment. These include: 1. Oral 17B-estradiol 2. Oral conjugated estrogens 3. 17B-estradiol patch (usually replaced every three to five days) 4. Estradiol valerate injection (typically every two weeks) 5. Estradiol cyp...

    By Route of Administration

    In general, transdermal or injected estrogen treatment is thought to be safer than oral treatment. This is because there is no hepatic first pass effect. Topical and injectable estrogens also need to be taken less often, which may make dealing with them easier. However, there are downsides to these options as well. It is easier for people to maintain steady levels of estrogen on pills than with other forms of estrogen. This can affect how some people feel when taking hormone treatment. Since...

    By Type of Estrogen

    Oral ethinyl estradiol is not recommended for use in transgender women because it is associated with an increased risk of blood clots. Conjugated estrogens are not used frequently, as they may put women at a higher risk of blood clots and heart attacks than 17B-estradiol, and they also cannot be accurately monitored with blood tests. Risk of thrombosis (blood clots) is particularly high for those who smoke. Therefore, it is recommended that if smokers wish to be on estrogen therapy, they use...

    Currently, many surgeons recommend that transgender women and transfeminine people stop taking estrogen before they undergo gender affirmation surgery. This is because of the potentially increased risk for blood clots that is caused both by estrogen and by being inactive after surgery. However, it is unclear whether this recommendation is necessary...

  2. Aug 4, 2018 · Transfeminine hormone therapy aims to achieve estradiol and testosterone levels within the normal female range. Commonly recommended ranges for transfeminine people in the literature are 100 to 200 pg/mL (367–734 pmol/L) for estradiol levels and less than 50 ng/dL (1.7 nmol/L) for testosterone levels (Table).

    • W Aly
    • 2018
  3. Jun 5, 2023 · Here are some of the most common results of estrogen-based HRT for transfeminine people: softer skin. breast growth. decreased muscle mass/growth. redistribution of body fat. thinning or slowed ...

  4. Accessing hormones through the NHS pathway involves getting a referral to a Gender Identity Clinic (GIC), from your GP or self referral if your chosen GIC accepts them, going onto a waiting list for many years to get an initial appointment, and then several months more waiting for a second appointment, at which point the GIC can make a recommendation for hormones for your GP to prescribe.

  5. Nov 30, 2017 · With growing numbers of transgender people presenting to healthcare services (estimated as 9.2 per 100 000 1), general practitioners, general endocrinologists, and other doctors will become increasingly involved in their long term care, the prescription of hormones, and consideration of potential side effects.

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  7. Mar 13, 2023 · Many trans women and transfeminine people look for ways to reduce facial and body hair. Although HRT also reduces and thins hair on the face and body, it can take 6 to 12 months to produce ...

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