Yahoo Web Search

Search results

1. • 

     thelancet.com

     • Synovial sarcoma differs from other STS by the relatively young age at diagnosis and clinical presentation. Synovial sarcomas have unique genomic characteristics and are driven by a pathognomonic t (X;18) chromosomal translocation and subsequent formation of the SS18:SSX fusion oncogenes.
     pubmed.ncbi.nlm.nih.gov/34069748/

     Synovial Sarcoma: A Clinical Review - PubMed

2. People also ask

   How is synovial sarcoma different from other STS?

   • Synovial sarcoma is unique from other STS as it presents at a younger mean age of onset and commonly occurs in adolescents and young adults (mean age of 39 years at diagnosis) and affects both sexes equally [ 5 ]. Synovial sarcoma is the most common non-rhabdomyosarcoma STS in children, representing 30% of STS diagnosed in childhood [ 4, 6 ]. 2.

   Synovial Sarcoma: A Clinical Review - PMC - National Center

   www.ncbi.nlm.nih.gov/pmc/articles/PMC8161765/

   See all results for this question

   What is a synovial sarcoma?

   • Keywords: clinical review; current concepts; soft tissue sarcoma; synovial sarcoma. Synovial sarcomas (SS) represent a unique subset of soft tissue sarcomas (STS) and account for 5-10% of all STS. Synovial sarcoma differs from other STS by the relatively young age at diagnosis and clinical presentation.

   Synovial Sarcoma: A Clinical Review - PubMed

   pubmed.ncbi.nlm.nih.gov/34069748/

   See all results for this question

   How common is synovial sarcoma (SS)?

   • Synovial sarcoma (SS) accounts for 5–10% of all STS [1, 2]. SS is an intriguing disease as, unlike the majority of STS, it can occur at any age and everywhere in the body. The peak incidence is in the 30s and it often presents in the extremities [3 •].

   Systemic Treatment for Adults with Synovial Sarcoma

   www.ncbi.nlm.nih.gov/pmc/articles/PMC5842271/

   See all results for this question

   Do orthopaedic surgeons recognize synovial sarcoma?

   • Given this unique presentation, it is important for orthopaedic surgeons to recognize synovial sarcoma and avoid inappropriate interventions. Synovial sarcomas have unique genomic characteristics and are driven by a pathognomonic t (X;18) chromosomal translocation and subsequent formation of the SS18:SSX fusion oncogenes.

   Free Full-Text | Synovial Sarcoma: A Clinical Review - MDPI

   www.mdpi.com/1718-7729/28/3/177

   See all results for this question

   What is the clinical presentation of synovial sarcoma?

   • Synovial sarcoma is one of the most common subtypes of soft-tissue sarcoma. The clinical presentation is non-specific and is most commonly due to the mass effect of a growing lesion. Synovial sarcoma does not typically present with specific symptoms.

   synovial cell sarcoma - statpearls - ncbi bookshelf

   www.ncbi.nlm.nih.gov/books/NBK587366/

   See all results for this question

   How is synovial sarcoma differentiated from other soft-tissue malignancies?

   • Synovial sarcoma (SS) can be distinguished from other soft-tissue malignancies by several features. It is characterized by the presence of TLE1 protein at 9q21.32, which is an excellent marker for SS. Additionally, SMARCB1/INI1 protein expression is reduced in SS. Synovial sarcoma typically arises from deep soft tissues of the extremities, but it can also arise less commonly from the trunk, thorax, and neck regions.

   synovial cell sarcoma - statpearls - ncbi bookshelf

   www.ncbi.nlm.nih.gov/books/NBK587366/

   See all results for this question

3. www.ncbi.nlm.nih.gov › pmc › articlesSynovial Sarcoma: A Clinical Review - PMC

   www.ncbi.nlm.nih.gov › pmc › articles

   May 19, 2021 · Synovial sarcoma differs from other STS by the relatively young age at diagnosis and clinical presentation. Synovial sarcomas have unique genomic characteristics and are driven by a pathognomonic t(X;18) chromosomal translocation and subsequent formation of the SS18:SSX fusion oncogenes.

   • Author: Aaron M. Gazendam, Snezana Popovic, Sohaib Munir, Naveen Parasu, David Wilson, Michelle Ghert
   • DOI: 10.3390/curroncol28030177

   • Publish Year: 2021
   • Publication: Curr Oncol. 2021 Jun; 28(3): 1909-1920.

4. www.ncbi.nlm.nih.gov › pmc › articlesSystemic Treatment for Adults with Synovial Sarcoma

   www.ncbi.nlm.nih.gov › pmc › articles

   Mar 7, 2018 · Synovial sarcoma (SS) is a rare, yet highly malignant, type of soft tissue sarcoma (STS), for which survival has not improved significantly during the past years. In this review, we focus on systemic treatment in adults. Compared to other STS, SS are relatively chemosensitive.

   • Author: Ingrid M. E. Desar, Emmy D. G. Fleuren, Winette T. A. van der Graaf

   • Publish Year: 2018

5. Videos

   • 

     4:26

     youtube.com

     Synovial Sarcoma: Paige's Mayo Clinic Story

     4 Mar 2016

     39K views

   • 

     6:02

     youtube.com

     Synovial Sarcoma (explained in 5 minutes): Soft Tissue Pathology Basics

     30 Aug 2022

     7.9K views

   • 

     34:01

     youtube.com

     Synovial Sarcoma 101…Explained by a Soft Tissue Pathologist

     19 Apr 2018

     34.5K views

   View all

6. pubmed.ncbi.nlm.nih.gov › 34069748Synovial Sarcoma: A Clinical Review - PubMed

   pubmed.ncbi.nlm.nih.gov › 34069748

   May 19, 2021 · Synovial sarcoma differs from other STS by the relatively young age at diagnosis and clinical presentation. Synovial sarcomas have unique genomic characteristics and are driven by a pathognomonic t(X;18) chromosomal translocation and subsequent formation of the SS18:SSX fusion oncogenes.

   • Author: Aaron M. Gazendam, Snezana Popovic, Sohaib Munir, Naveen Parasu, David Wilson, Michelle Ghert

   • Publish Year: 2021

7. www.mdpi.com › 1718/7729/28-3 › 177Synovial Sarcoma: A Clinical Review - MDPI

   www.mdpi.com › 1718/7729/28-3 › 177

   • Cached

   May 19, 2021 · Synovial sarcoma differs from other STS by the relatively young age at diagnosis and clinical presentation. Synovial sarcomas have unique genomic characteristics and are driven by a pathognomonic t(X;18) chromosomal translocation and subsequent formation of the SS18:SSX fusion oncogenes.

   • Author: Aaron M. Gazendam, Snezana Popovic, Sohaib Munir, Naveen Parasu, David Wilson, Michelle Ghert

   • Publish Year: 2021

8. Images

   • 
   • 
   • 
   • 

   View all

9. www.researchgate.net › publication › 351732367(PDF) Synovial Sarcoma: A Clinical Review - ResearchGate

   www.researchgate.net › publication › 351732367

   May 19, 2021 · Synovial sarcoma differs from other STS by the relatively young age at diagnosis and clinical presentation. Synovial sarcomas have unique genomic characteristics and are driven by a...

10. pubmed.ncbi.nlm.nih.gov › 29516254Systemic Treatment for Adults with Synovial Sarcoma - PubMed

    pubmed.ncbi.nlm.nih.gov › 29516254

    Mar 7, 2018 · Synovial sarcoma (SS) is a rare, yet highly malignant, type of soft tissue sarcoma (STS), for which survival has not improved significantly during the past years. In this review, we focus on systemic treatment in adults. Compared to other STS, SS are relatively chemosensitive.

11. www.ncbi.nlm.nih.gov › books › NBK587366Synovial Cell Sarcoma - StatPearls - NCBI Bookshelf

    www.ncbi.nlm.nih.gov › books › NBK587366

    May 6, 2023 · Synovial sarcoma (SS) is a mesenchymal tumor with partial epithelial differentiation. It is commonly seen in older children and younger adults. The presence of t(X;18)(p11.2;q11.2) is a pathognomonic feature of synovial sarcoma.