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  2. Does milk thistle interact with my other drugs? Enter other medications to view a detailed report.

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  3. Sep 9, 2015 · Milk thistle is a widely used herbal product that appears to have a relatively low risk of drug interactions. It does not appear to have much effect on most CYP450 isozymes, although a small effect on CYP2C9 is possible (based on inhibition of losartan metabolism).

  4. In some cases, specific interactions between milk thistle and certain anti-anxiety drugs have been documented. For example, studies have shown that milk thistle may affect the metabolism of benzodiazepines, potentially altering their concentration in the body.

  5. Aug 10, 2023 · Taking milk thistle might affect this enzyme and drugs it processes, such as diazepam (Valium), warfarin (Jantoven) and others. This means milk thistle might affect the levels of these drugs in your body.

  6. Indinavir (Crixivan) interacts with MILK THISTLE. Indinavir is a drug that is changed and broken down by the liver. Milk thistle might increase how quickly the liver breaks down some medications.

  7. What other drugs will affect milk thistle? Do not take milk thistle without medical advice if you are using a medication to treat any of the following conditions: any type of infection (including HIV, malaria, or tuberculosis); anxiety or depression; arthritis pain, occasional pain, or tension headaches (including Advil, Motrin, or Celebrex);

  8. Feb 28, 2024 · Milk thistle does not have any documented significant drug-drug interactions. However, since it does exert some effect on the CYP450 enzyme system, it might affect certain drugs, including diazepam and warfarin.

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