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Supercoiled chromosome is relaxed by topoisomerase II
semanticscholar.org
- For bacterial DNA replication to begin, the supercoiled chromosome is relaxed by topoisomerase II, also called DNA gyrase. An enzyme called helicase then separates the DNA strands by breaking the hydrogen bonds between the nitrogenous base pairs.
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Feb 17, 2023 · DNA replication starts at a particular location on the DNA, called the origin of replication. It is the region where the DNA is unzipped. They have a specific sequence covering about 245 base pairs, mostly A/T base pairs and fewer GT-base pairs.
Apr 21, 2024 · Explain why DNA replication is bidirectional and includes both a leading and lagging strand. Explain why Okazaki fragments are formed. Describe the process of DNA replication and the functions of the enzymes involved. Identify the differences between DNA replication in bacteria and eukaryotes.
May 1, 2007 · Bacteria use many regulatory strategies that are dedicated to controlling the initiation of DNA replication. Among these, origin sequestration, DnaA titration, dnaA autoregulation and DnaA...
- Melissa L. Mott, James M. Berger
- 2007
We have seen how two replication forks begin at a single replication origin in bacteria and proceed in opposite directions, moving away from the origin until all of the DNA in the single circular chromosome is replicated.
- Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter
- 2002
- 2002
Still, even in bacteria, with their smaller genomes, DNA replication involves an incredibly sophisticated, highly coordinated series of molecular events. These events are divided into four major...
Jun 20, 2023 · Cellular control of replication in bacteria. We have seen that the initiator protein DnaA and the replicator element oriCare needed for the initiation of replication, and that the slow rate of methylation at GATC motifs prevents re-initiation for some time. The bacterial cell can sense when the nutritional conditions, levels of nucleotide pools ...
Aug 31, 2023 · DNA replication (arrows) occurs in both directions from the origin of replication in the circular DNA found in most bacteria. All the proteins involved in DNA replication aggregate at the replication forks to form a replication complex called a replisome.
