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We have structured the results in two different categories: Observed and Expected. “Observed” are counts of database matches and “Expected” are approximations/estimates of Haplotype frequencies revealed by biostatistical calculations.
The “Discrete Laplace method” which is implemented in the Y Chromosome Haplotype Reference Database (YHRD) is a model-based extrapolation method which makes use of an in-depth analysis of Y-STR profiles in more than thousand worldwide population samples.
YHRD is built by direct submissions of population data from individual laboratories. Upon receipt of a submission, the YHRD staff examines the originality, relevance, plausibility and validity of the data and assigns an accession number to the population sample if these criteria are met.
- 3.4 Help & Support
- 3.4.1 Contribute
- 4.3.1 Counting
- 4.3.2 Augmented counting
- 4.4.2 MDS (Multidimensional scaling)
Sascha Willuweit: sascha.willuweit@charite.de Lutz Roewer: lutz.roewer@charite.de
The YHRD offers a number of help and support pages which include this manual, a screencast, FAQs, videos and links to educational webinars.
This page explains in detail the submission of population samples to the YHRD and the procedure to receive an accession number (mandatory for peer-reviewed publication).
The observed match count in a database is used as the frequency estimate. The method is limited by the database size.
The frequency of a haplotype when adding the haplotype in question once to both the database and the observations. The method is limited by the database size.
This analysis is used to assign pair-wise similarities (or dissimilarities) to points in an N-dimensional space representing those similarities as distances between points. There are two major principles of MDS: Metric MDS (M-MDS), a distance matrix D (similarities) into a set of coordinates such that the Euclidean distances derived from these coor...
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YHRD : Y-Chromosome STR Haplotype Reference Database. Aim & Objectives. Generate reliable Y-STR haplotype frequency estimates for Y-STR haplotypes to be used in the quantitative assessment of matches in forensic and kinship casework.
YHRD (www.yhrd.org) is an online Y chromosome haplotype reference database built from an initial collaboration with 31 forensic and anthropological institutions across Europe who contributed almost 5000 male minimal haplotypes to the collection initiated by academics at the Charité University in Berlin; the database went live in 2000 . Since ...
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Mar 1, 2015 · Y chromosome STR profiling is the most advanced method to analyze the male proportion of female/male cell mixtures. In addition a combination of Y-STRs and Y-SNPs provides valuable investigative leads on the geographical ancestry of the male trace donor.
