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      • ER stress responses mitigate the damage caused by stress and confer levels of stress tolerance to plants. ER stress is activated by misfolded proteins that accumulate in the ER under adverse environmental conditions.
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  2. Mar 18, 2024 · The past decades have seen notable progress in understanding the mechanisms underlying ER stress sensing and signalling transduction pathways, implicating the UPR in the effects of...

  3. Apr 15, 2013 · Plants maintain a balance between protein folding demand and folding capacity. When that balance is disturbed by conditions, such as environmental stress, unfolded and misfolded proteins accumulate in the ER, causing “ER stress”, a condition, which can do damage to cells.

    • Yan Deng, Renu Srivastava, Stephen H. Howell
    • 10.3390/ijms14048188
    • 2013
    • Int J Mol Sci. 2013 Apr; 14(4): 8188-8212.
  4. A wide range of stresses affect protein folding, causing ER stress that is communicated to the nucleus via the UPR, a cellular homeostatic response to ER stress [106,107]. As a result, genes involved in the folding, import, export, and quality control of proteins are up-regulated.

  5. Endoplasmic reticulum (ER) stress is of considerable interest to plant biologists because it occurs in plants subjected to adverse environmental conditions. ER stress responses mitigate the damage caused by stress and confer levels of stress tolerance to plants.

    • Stephen H Howell
    • 2013
  6. Apr 5, 2021 · It comes to mind when observing the endoplasmic reticulum (ER) in live plant cells and reflecting on the ability of this organelle to respond and adapt to the changing biosynthetic demands of the cell during growth and in response to stress.

    • Federica Brandizzi, Federica Brandizzi
    • 2021
  7. Plants are considered to be under stress when environmental conditions are not ideal for growth. How adverse environments affect plant growth is not only a fundamental scientific question but is also of vital importance for agriculture and food security.

  8. Apr 15, 2013 · The endoplasmic reticulum (ER) stress response is a highly conserved mechanism that results from the accumulation of unfolded or misfolded proteins in the ER. The response plays an important role in allowing plants to sense and respond to adverse environmental conditions, such as heat stress, salt s ….

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