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- Some pathogens avoid the immune system by hiding within the cells of the host, a process referred to as intracellular pathogenesis. Other pathogens invade the body by changing the non-essential epitopes on their surface rapidly, while keeping the essential epitopes hidden.
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Many pathogens also deploy diverse immune evasion tactics in the host to achieve host cell invasion and colonisation and may successfully exploit host cells to access target tissues.
- Virus Replication
As viruses are obligate intracellular pathogens they cannot...
- Human Immunodeficiency Virus (Hiv)
Human immunodeficiency virus (HIV), a member of the...
- Malaria
Key facts. With an estimated 216 million cases annually...
- Tuberculosis
The first cells encountered by the mycobacteria in the lung...
- Virus Replication
Every 2–3 years, a variant arises with mutations that allow the virus to evade neutralization by antibodies in the population; other mutations affect epitopes that are recognized by T cells and, in particular, CD8 T cells, so that cells infected with the mutant virus also escape destruction.
- Charles A Janeway, Paul Travers, Mark Walport, Mark J Shlomchik
- 2001
- 2001
Here we highlight emerging themes from the recent literature, from evasion mechanisms by which pathogens avoid antimicrobial molecules, to the ability of pathogens to directly modulate innate immune signal transduction pathways, and immune receptor localization and cytokine secretion.
Dec 24, 2022 · Some pathogens avoid the immune system by hiding within the cells of the host, a process referred to as intracellular pathogenesis. Other pathogens invade the body by changing the non-essential epitopes on their surface rapidly, while keeping the essential epitopes hidden.
Aug 31, 2023 · Antibodies, such as IgG, IgA, and IgM, can bind to bacterial adhesins, pili, and capsules and in this way block their attachment to host cells. c. IgG and IgM can also activate the classical complement pathway providing all of its associated benefits.
Dec 11, 2019 · Lee and coworkers provide a comprehensive summary of viral strategies that evade host cytosolic sensing to facilitate intracellular infection and replication of viruses.
Nov 1, 2002 · The success of many pathogens relies on their ability to circumvent, resist or counteract host defense mechanisms; yet some bacteria also provoke activation of the immune system,...
