Search results
People also ask
How do mechanical nociceptors respond?
How do nociceptors respond to pain?
What types of nociceptors respond to heat?
How do noxious stimuli trigger nociceptors?
How do nociceptors respond to injury?
What is nociception & how does it work?
Nociceptors respond to certain temperature range and mechanical stimulus. The peripheral end of the axon contains encapsulated proteins called transduction proteins (TRP), which can be activated by a specific stimulus.
May 1, 2023 · Acute noxious stimuli (e.g., heat, cold, mechanical force, or chemical stimulation) trigger nociceptors. Acute pain becomes inflammatory pain when the noxious stimulus persists long enough to allow nociceptive neurons to release their pro-inflammatory markers and sensitize or activate responsive cells in their local environment.
- Scott A. Armstrong, Michael J. Herr
- 2023/05/01
- University of Tennessee HSC, UTHSC
Mechanical nociceptors respond to excess pressure or mechanical deformation. They also respond to incisions that break the skin surface. The reaction to the stimulus is processed as pain by the cortex, just like chemical and thermal responses.
Sep 13, 2001 · Nociceptors can be activated by mechanical stress resulting from direct pressure, tissue deformation or changes in osmolarity, enabling the detection of touch, deep pressure, distension...
- David Julius, Allan I. Basbaum
- 2001
A nociceptor is a type of receptor that signals potentially harmful stimuli in the tissue, categorized into mechanoreceptors, mechanical/thermal receptors, and polymodal receptors responsive to various stimuli. These receptors supply both unmyelinated C fibers and myelinated fibers, contributing to the perception of 'first pain' and 'second pain'.
Sep 26, 2022 · Joint nociceptors are classified as high-threshold mechanoreceptors, polymodal receptors, and silent receptors. Silent receptors are unresponsive to the initial stimuli of heat or pressure, but they become responsive only after tissue damage causes the release of inflammatory molecules.
In general, the faster-conducting Aδ nociceptors respond either to dangerously intense mechanical or to mechanothermal stimuli, and have receptive fields that consist of clusters of sensitive spots. Other unmyelinated nociceptors tend to respond to thermal, mechanical, and chemical stimuli, and are therefore said to be polymodal .
