Search results
Increases the risk of rare serious infections
- Adalimumab increases the risk of rare serious infections. There is a two-fold risk of serious infections with the use of adalimumab, as reported in the Premier trial. This risk should not be minimised in this way. It should not be used during periods of active infection. Its most notable infectious complication is the reactivation of tuberculosis.
pubmed.ncbi.nlm.nih.gov/16011443/
you get infections, including a high temperature, chills, increased sweating, feeling unwell or more tired than normal, diarrhoea, coughing up blood or mucus, shortness of breath, problems peeing, skin sores, wounds or muscle aches – these could be signs of a severe infection.
If your immune system is affected by adalimumab, you're more at risk of infection caused by a live vaccine. If you need to have a vaccine, check with your doctor, pharmacist or nurse whether it's a live vaccine and if there's an alternative, non-live vaccine available.
Adalimumab can make you more likely to get infections. Tell your doctor if you get an infection, such as coronavirus (COVID-19), or if you come into contact with anyone who has shingles, chickenpox or measles.
Jul 24, 2024 · Patients treated with adalimumab are at increased risk of infection, some of which may become serious and lead to hospitalization or death. These infections have included TB, invasive fungal infections, bacterial, viral, and those caused by opportunistic pathogens including Legionella and Listeria.
- (672)
- Consultant Pharmacist
Associated with infections, sometimes severe, including tuberculosis, septicaemia, and hepatitis B reactivation. Conception and contraception Manufacturer advises effective contraception required during treatment and for at least 5 months after last dose.
Jun 11, 2024 · Adalimumab works by blocking a protein called tumor necrosis factor (TNF) that can cause inflammation, pain, or other autoimmune symptoms. Adalimumab is from a class of medicine called TNF alfa inhibitor. There are 10 biosimilars of Humira, the brand names are Abrilada, Amjevita, Cyltezo, Hadlima, Hulio, Idacio, Yuflyma, and Yusimry.
Feb 27, 2024 · Adalimumab is an immunosuppressant and can lower the ability of your immune system to fight bacterial, viral, or fungal infections or make an infection worse. It may cause some infections, such as tuberculosis, to become active again.
