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  2. Oct 21, 2020 · Intervention: Valeriana edulis (dried and crushed whole root, containing 1.1% of valtrate/isovaltrate) 20mg/kg body weight, nightly 1 h before bedtime for 2 weeks. Wash-out 7 days. Measures: Sleep latency, time spent awake during the night, and sleep quality (VAS).

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      Intervention: Valeriana edulis (dried and crushed whole...

  3. Extracts of the roots of valerian (Valeriana officinalis) are widely used for inducing sleep and improving sleep quality. A systematic review of randomized, placebo-controlled trials of valerian for improving sleep quality is presented. An extensive literature search identified 16 eligible studies examining a total of 1093 patients.

  4. Oct 4, 2005 · Extracts of the roots of valerian (Valeriana officinalis) are widely used for inducing sleep and improving sleep quality. A systematic review of randomized, placebo-controlled trials of valerian for improving sleep quality is presented.

    • Stephen Bent, Stephen Bent, Amy Padula, Dan Moore, Michael Patterson, Wolf Mehling
    • 2006
  5. Jun 1, 2007 · One study of an aqueous valerian extract showed reduced sleep onset latency by wrist actigraphy in persons with sleep onset insomnia. 38 However, sleep latency was not longer than 30 min at baseline (15 min) and on average was reduced only four to six minutes, providing only weak evidence of valerian sedation. Overall, these findings do not ...

    • Diana M. Taibi, Carol A. Landis, Heidi Petry, Michael V. Vitiello
    • 2007
  6. May 1, 2024 · Scientific evidence regarding the efficacy of valerian is inconclusive. Valerian has been reported to reduce subjective sleep latency (SL) and reduce slow wave sleep at a dose of 300 mg per day for two weeks (Donath et al., 2000).

  7. Oct 21, 2020 · Three studies investigated the effectiveness of other Valeriana spp. as a sleep aid: 2 studies on V. edulis 42,46 and 1 study on V. wallichii. 70 V. edulis 20 mg/kg for 2 weeks reduced sleep latencies and improved sleep quality in children with intellectual deficit and primary sleep problems 46 (RCT [Jadad scale 5]), and V. edulis ...

  8. Jun 16, 2023 · In this study, we examined the effects of valerian on sleep quality, latency, duration, efficiency or next-day functioning, the number of awakenings, wake after sleep onset, NREM stages 1–4, REM sleep-onset latency, and REM sleep duration by a systemic review and meta-analysis.

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