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   When is Mirabegron contraindicated?

   • Mirabegron is now contraindicated in patients with severe uncontrolled hypertension defined as systolic blood pressure ≥180 mm Hg and/or diastolic blood pressure ≥110 mm Hg. Measure blood pressure before starting treatment and monitor it regularly during treatment, especially in patients with hypertension.

   Mirabegron (Betmiga ) - new recommendations about the risk of increase

   assets.publishing.service.gov.uk/media/561cda83ed915d39bc000011/Betmiga_DHPC_UK_FINAL_MHRA_approved_to_HCPs_04Sept15.pdf

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   Can Mirabegron be used in patients with Stage 2 hypertension?

   • Regular monitoring of blood pressure is important, especially in patients with pre-existing hypertension. Data are limited regarding use of mirabegron in patients with stage 2 hypertension (ie, systolic blood pressure ≥160 mm Hg or diastolic blood pressure ≥100 mm Hg) and it should therefore be used with caution in this group.

   Mirabegron (Betmiga ): risk of severe hypertension and associated

   www.gov.uk/drug-safety-update/mirabegron-betmiga-risk-of-severe-hypertension-and-associated-cerebrovascular-and-cardiac-events

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   Does Mirabegron cause hypertension?

   • Serious cases of hypertension and increased blood pressure have been reported in patients on mirabegron treatment. In addition, there have been some reports of hypertensive crisis and cerebrovascular and cardiac events associated with hypertension with a clear temporal relationship with the use of mirabegron.

   Mirabegron (Betmiga ) - new recommendations about the risk of increase

   assets.publishing.service.gov.uk/media/561cda83ed915d39bc000011/Betmiga_DHPC_UK_FINAL_MHRA_approved_to_HCPs_04Sept15.pdf

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   Is Mirabegron contraindicated in patients with hypertension?

   • Mirabegron is now contraindicated in patients with severe uncontrolled hypertension (systolic blood pressure ≥180 mm Hg or diastolic blood pressure ≥110 mm Hg, or both). Regular monitoring of blood pressure is important, especially in patients with pre-existing hypertension.

   Mirabegron (Betmiga ): risk of severe hypertension and associated

   www.gov.uk/drug-safety-update/mirabegron-betmiga-risk-of-severe-hypertension-and-associated-cerebrovascular-and-cardiac-events

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   What are the side effects of Mirabegron?

   • You or the person who's unwell may also have a rash that's swollen, raised, itchy, blistered or peeling. These can be signs of a serious allergic reaction and may need immediate treatment in hospital. Do not drive yourself to A&E. The person you speak to at 999 will give you advice about what to do. These are not all the side effects of mirabegron.

   Side effects of mirabegron - NHS

   www.nhs.uk/medicines/mirabegron/side-effects-of-mirabegron/

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   What should I know before taking Mirabegron?

   • Avoid concurrent use, or reduce the starting dose of mirabegron in people with hepatic or renal impairment who are also taking a strong cytochrome P450 inhibitor. Monitor blood pressure before starting treatment and regularly during treatment, especially in people with pre-existing hypertension.

   Mirabegron | Prescribing information | LUTS in men | CKS - NICE

   cks.nice.org.uk/topics/luts-in-men/prescribing-information/mirabegron/

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2. www.gov.uk › drug-safety-update › mirabegron-betmigaMirabegron (Betmiga ): risk of severe hypertension and ...

   www.gov.uk › drug-safety-update › mirabegron-betmiga

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   Oct 14, 2015 · Mirabegron is now contraindicated in patients with severe uncontrolled hypertension (systolic blood pressure ≥180 mm Hg or diastolic blood pressure ≥110 mm Hg, or both).

3. www.medicinesresources.nhs.uk › en › MedicinesMirabegron (Betmiga ): risk of severe hypertension and ...

   www.medicinesresources.nhs.uk › en › Medicines

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   It is already known that mirabegron can increase blood pressure. Cases of severe hypertension have been reported including hypertensive crisis associated with reports of cerebrovascular and cardiac events (mainly transient ischaemia attack or stroke).

4. www.nhs.uk › medicines › mirabegronSide effects of mirabegron - NHS

   www.nhs.uk › medicines › mirabegron

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   Common side effects. These common side effects of mirabegron are usually mild and do not last long. There are things you can do to help cope with them: Feeling sick (nausea) Try taking mirabegron with food. It may also help if you stick to simple meals and avoid rich or spicy food. Constipation.

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6. pmc.ncbi.nlm.nih.gov › articles › PMC9228850Impact of Mirabegron Administration on the Blood Pressure and ...

   pmc.ncbi.nlm.nih.gov › articles › PMC9228850

   Conclusions: Mirabegron does not have any adverse effects on BP and PR. However, since some patients in this study had elevated SBP after administration, we suggest regular BP monitoring during mirabegron treatment. Keywords: blood pressure, pulse rate, mirabegron, overactive bladder. 1. Introduction

7. cks.nice.org.uk › mirabegronMirabegron | Prescribing information | LUTS in men | CKS - NICE

   cks.nice.org.uk › mirabegron

   Severe uncontrolled hypertension (systolic blood pressure 180 mmHg or higher and/or diastolic blood pressure 110 mmHg or higher). Prescribe mirabegron with caution to people with: A history of QT-interval prolongation, or taking medicines known to cause QT-interval prolongation.

8. bnf.nice.org.uk › drugs › mirabegronMirabegron | Drugs | BNF | NICE

   bnf.nice.org.uk › drugs › mirabegron

   Severe uncontrolled hypertension (systolic blood pressure ≥180 mmHg or diastolic blood pressure ≥110 mmHg)

9. assets.publishing.service.gov.uk › media › 561cda83Mirabegron (Betmiga ) - new recommendations about the risk of ...

   assets.publishing.service.gov.uk › media › 561cda83

   Serious cases of hypertension and increased blood pressure have been reported in patients on mirabegron treatment. Mirabegron is now contraindicated in patients with severe uncontrolled...