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  2. There are 4 drugs known to interact with milk thistle. Of the total drug interactions, 3 are moderate, and 1 is minor.

    • (7)
  3. If you take allergy meds, be careful with milk thistle. Talk to a doctor before using it with your meds. It might affect how your allergy meds work. A study showed that people with ragweed allergies used fewer meds after taking milk thistle.

  4. Aug 10, 2023 · Milk thistle can cause an allergic reaction, including a severe, potentially life-threatening allergic reaction (anaphylaxis). An allergic reaction is more common in people who are allergic to other plants in the Asteraceae family, such as ragweed, daisies, marigolds and chrysanthemums.

  5. Milk thistle may interfere with the following medications, because both milk thistle and these medications are broken down by the same liver enzymes: Allergy drugs -- such as fexofenadine (Allegra) Drugs for high cholesterol -- such as lovastatin (Mevacor, Altocor)

  6. Sep 9, 2015 · Inhibition of glucuronidation by milk thistle may be the most likely mechanism for clinically important drug interactions, but supporting clinical data are needed before specific action can be recommended.

  7. Contraindications. Milk Thistle for Allergies. What is Milk Thistle? Milk Thistle is a flowering plant that has been used for centuries to treat a variety of health issues, including liver problems and digestive issues. The plant’s seeds contain a unique compound called silymarin, which is responsible for its medicinal properties.

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