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Jan 17, 2000 · High doses can cause chronic wounding of tissues, cell death and consequent chronic cell division of neighboring cells, which is a risk factor for cancer. Each time a cell divides, there is some probability that a mutation will occur, and thus increased cell division increases the risk of cancer.
- Bruce N Ames, Lois Swirsky Gold
- 2000
Feb 23, 2021 · The main purpose of this article is to highlight the great impact of Paracelsus, a German-Swiss alchemist and physician of the 16th century, on toxicology. Paracelsus is recognized as the most influential medical scientist in Western Europe during the Renaissance.
- Spyros N. Michaleas, Konstantinos Laios, Gregory Tsoucalas, Georges Androutsos
- 10.1016/j.toxrep.2021.02.012
- 2021
- Toxicol Rep. 2021; 8: 411-414.
In fact, by defining that a (lower) dose will prevent adverse effects, Paracelsus laid the groundwork for the modern separation of the terms hazard and risk. I shall further discuss these issues below.
- Philippe Grandjean
- 10.1111/bcpt.12622
- 2016
- 2016/08
Jun 28, 2010 · With environmental, dietary, and endogenous exposures to formaldehyde, epidemiological studies on formaldehyde are warranted, and the integration of basic mechanistic data with the epidemiological findings are critical to developing sound human cancer risk assessments for this high-volume chemical.
- Lois Lehman-McKeeman
- 2010
Aug 7, 2009 · Reform and purification—a process also linked to alchemy—would precede the End Time. Paracelsus personally felt the force of the Gospel's Great Commission: his bodily healing and reform of bodily healing were the natural side of the spiritual healing and reform of the true, supernatural Church.
- Joseph P. Byrne
- 2010
There is no cancer epidemic other than that due to smoking. The dose makes the poison. Half of all chemicals tested, whether natural or synthetic, cause cancer in high-dose ro-dent cancer tests. Evidence suggests that this high rate is due primarily to effects that are unique to high doses.
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An interesting thesis maintained by Paracelsus was the doctrine that every disease must have its remedy. The scholastic authorities had pronounced certain diseases as incurable, and they were accordingly so considered by the profession. Rejecting as he did the ancient authorities, Paracelsus naturally enough rejected this dogma as neces sarily ...
