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Muscle is a tool for aligning up to 500 sequences or a maximum file size of 1 MB. It claims to achieve better accuracy and speed than other tools, depending on the chosen options.
Muscle is a widely-used tool for making alignments of biological sequences or structures with high accuracy and speed. It can generate replicate alignments and compare downstream predictions to assess alignment robustness.
MUSCLE is a public domain software that aligns protein and nucleotide sequences using a progressive and refinement algorithm. It is faster and more accurate than Clustal, and can be integrated into various bioinformatics tools and platforms.
Nov 12, 2021 · MUSCLE v5 is a major re-write of MUSCLE based on new algorithms. It can align tens of thousands of sequences with high accuracy and generate ensembles of alternative alignments.
MUSCLE is a public domain tool that creates multiple alignments of amino acid or nucleotide sequences. It offers options to optimize accuracy, speed, or both, and provides a manual and a citation.
Aug 19, 2004 · MUSCLE is a program for creating multiple alignments of protein sequences, using a progressive and refinement approach. It offers improved speed and accuracy compared with other methods, and has a new option for high-throughput applications.
People also ask
How can a multiple alignment be obtained?
Does muscle support alternative alignments?
What is multiple sequence comparison by Log-Expectation (MUSCLE)?
What is a progressive alignment?
Why is multiple sequence alignment important?
What is muscle & how does it work?
Nov 15, 2022 · I describe Muscle5, a novel algorithm which constructs an ensemble of high-accuracy alignment with diverse biases by perturbing a hidden Markov model and permuting its guide tree.
