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Jul 3, 2023 · Highly active antiretroviral therapy (HAART) is a medication regimen used to manage and treat human immunodeficiency virus type 1 (HIV-1). It is composed of several drugs in the antiretroviral classes of medications. This activity outlines the indications, mechanism of action, and contraindications for various HAART medications in the ...
- Julie S. Eggleton, Shivaraj Nagalli
- 2023/07/03
- 2021
- Background
- How Antiretrovirals Works
- Drug Classes
- Benefits
- A Word from Verywell
- GeneratedCaptionsTabForHeroSec
Prior to HAART, the use of one or two antiretroviral drugs afforded limited control of the virus, resulting in rapid treatment failure and the development of multi-drug resistance. It was with the introduction of a class of drugs called protease inhibitors in 1995 that doctors were able to combine three or more drugs in a way that stopped HIV from ...
Antiretroviral drugs do not kill HIV; rather, they block different stages in the virus's life cycle—from the time it attaches to a cell to the time it creates new copies of itself to infect other cells. The combination of drugs works as something of a biological "tag team," suppressing a wide range of HIV variants that can exist within a single pop...
In the past, HAART was equated to triple-drug therapy. Today, because of improved pharmacokinetics, some antiretroviral therapies consist of only two drugs. There are currently six classes of antiretroviral drugs able to treat HIV, each of which inhibits a specific stage in the virus's life cycle: 1. Entry/attachment inhibitors 2. Non-nucleoside re...
In addition to preventing disease progression in people with HIV, the widespread use of antiretrovirals can reverse infection rates in many high-risk populations. The strategy, known as treatment as prevention, aims to reduce the "community viral load" within a population, making it more difficult to spread infection. The same aims can be achieved ...
HAART altered the course of the AIDS pandemic in the late-20th and early-21st centuries. The benefits extended not only to people with HIV but to others around them. Today, antiretrovirals can even be used in non-infected people to further reduce their risk of infection. By taking one pill a day, an HIV-negativeperson can reduce their risk of getti...
HAART stands for highly active antiretroviral therapy, a combination of drugs that blocks different stages of HIV replication. Learn how HAART works, its benefits, and the different classes of antiretroviral drugs.
- Mark Cichocki, RN
Jul 9, 2023 · Learn how HAART (highly active antiretroviral therapy) became ART (antiretroviral therapy) and how the treatment of HIV has changed over time. Find out the benefits, challenges, and advances of HIV drugs from AZT to Viread.
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Jul 3, 2023 · Highly active antiretroviral therapy (HAART) is a medication regimen used to manage and treat human immunodeficiency virus type 1 (HIV-1). It is composed of several drugs in the antiretroviral classes of medications.
