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  1. Mar 24, 2018 · Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are enzymes found within liver cells at high concentrations. Raised ALT / AST levels in the blood occur in pathologies that cause liver cell (hepatocyte) inflammation or damage.

  2. May 1, 2024 · Marked elevations of ALT or AST (greater than 1,000 IU/L) suggest drug-induced liver injury (such as paracetamol overdose), acute viral hepatitis, ischaemic, or autoimmune hepatitis and may require referral to secondary care for further follow up.

  3. Feb 14, 2023 · There are three main lab values that are commonly evaluated in relation to liver health: aspartate aminotransferase (AST), alanine transaminase (ALT) and alkaline phosphatase (ALP). AST and ALT are markers of liver cell injury.

  4. Aug 13, 2024 · ALT and AST are liver enzymes produced by the liver. If you have high levels of ALT and AST in your blood, it could be a sign of liver disease. The ratio of ALT to AST can help diagnose the underlying cause.

  5. Dec 1, 2017 · Mild, asymptomatic elevations of alanine transaminase (ALT) and aspartate transaminase (AST) levels, defined as less than five times the upper limit of normal, are common in primary care.

  6. Mild isolated elevations of alanine aminotransferase (ALT) or aspartate aminotransferase (AST; < 2 times normal) may require only repeat testing; they resolve in about one third of cases.

  7. Jul 31, 2024 · Mixed/infiltrative (elevation of both ALT/AST and ALP). Isolated elevation of liver tests is a less common occurrence in liver diseases, and a non-hepatic source should be considered in such instances.

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