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Maurice Ralph Hilleman (August 30, 1919 – April 11, 2005) was a leading American microbiologist who specialized in vaccinology and developed over 40 vaccines, an unparalleled record of productivity.
- Vaccines
- Hilleman’S First Vaccine
- Preventing An Influenza Pandemic
- Dozens of New Vaccines
- New Discoveries
- Some Personal Details and The End
Maurice Hilleman was the greatest inventor of vaccines the world has ever known. His vaccines were based on the idea used by earlier scientists such as Louis Pasteur, that you could take a virus and weaken it. The virus would then be too weak to cause disease, but would push people’s immune systems into producing natural antibodies. These antibodie...
Hilleman joined the pharmaceutical company E. R. Squibb in New Jersey in 1944. He developed an effective vaccine against Japanese B encephalitis and worked on the mass production of influenza vaccine.
In 1948, age 28, Hilleman moved to Washington, D.C. to join the Department of Respiratory Diseases at Army Medical Center. There he became an authority on mutation in influenza viruses, observing two different mechanisms for genetic changes in influenza: drift, a gradual annual change in the virus; and shift, a less frequent but more dramatic chang...
In 1957, age 38, Hilleman was recruited by the pharmaceutical company Merck & Co. He moved to West Point, Pennsylvania, from where he would lead Merck’s virus and vaccination research programs for the next 45 years. At Merck he had unprecedented success, inventing a series of highly effect new vaccines to protect people against measles, mumps, rube...
Hilleman was the discoverer or co-discoverer of several viruses. These included hepatitis A, SV40, and a number of adenoviruses and rhinoviruses. He was the first scientist to purify the drug interferon and he discovered that interferon’s expression is induced by double-stranded RNA.
In 1943, age 23, Hilleman married Thelma Mason with whom he had two daughters, Jeryl Lynn and Kirsten. Thelma died in 1962. In 1963 Hilleman married Lorraine Witmer. Hilleman had a reputation as a tough and at times ill-tempered man. He worked seven-day weeks and expected people he directed at Merck to do likewise. Anyone who didn’t measure up to h...
Aug 27, 2016 · Maurice Ralph Hilleman (1919–2005) was one of the greatest microbiologists/vaccinologists of all time. He played a key role in developing vaccines for Asian flu in 1957 and Hong Kong flu in 1968.
- Theodore H. Tulchinsky, Theodore H. Tulchinsky
- 10.1016/B978-0-12-804571-8.00003-2
- 2018
- 2018
Sadly, his wife, Thelma, died in 1963. Dr. Hilleman married Lorraine Witmer the following year. They had a daughter, Kirsten, in 1965. While at Merck, Dr. Hilleman developed vaccines to protect us from chickenpox, hepatitis A, hepatitis B, pneumococcus, meningococcus, measles, mumps, and rubella.
May 6, 2013 · At 1 a.m. on March 21, 1963, an intense, irascible but modest Merck scientist named Maurice R. Hilleman was asleep at his home in the Philadelphia suburb of Lafayette Hill when his 5-year-old...
May 29, 2020 · You could do your research,” Hilleman’s second wife Lorraine Witmer once told Hilleman’s biographer. By working in the private sector—the “dirty industry” as Hilleman joked—he was ...
Apr 28, 2005 · Microbe hunter, pioneering virologist, and the 20th century's leading vaccinologist. Maurice Hilleman was responsible for developing more than 40 vaccines, including measles, mumps, hepatitis A, hepatitis B, meningitis, pneumonia, Haemophilus influenzae bacteria, and rubella.
