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Sergio CASTRO-GOMEZ, Researcher | Cited by 332 | of Deutsches Zentrum für Neurodegenerative Erkrankungen, Bonn (DZNE) | Read 20 publications | Contact Sergio CASTRO-GOMEZ.
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Sergio CASTRO-GOMEZ, Researcher | Cited by 332 | of...
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Nov 17, 2021 · We propose that cardiac troponin T elevations in amyotrophic lateral sclerosis are of non-cardiac origin and may serve as a proxy of lower motor neuron or skeletal muscle involvement. They potentially help to stratify patients according to lower motoneuron involvement.
Dec 31, 2023 · Serum cardiac Troponin T (cTnT), widely in use as a serum marker of myocardial injury, has recently emerged as a promising candidate serum biomarker for ALS, correlating with disease severity and progression6,7. Accumulating evidence suggests that degenerating or regenerating skeletal muscle is an.
Dr. Dr. med. Sergio Castro-Gomez (MD-PhD) Clinic for Neurodegenerative Diseases - Gerontopsychiatry. Sergio Castro-Gomez studied medicine at the Universities of Antioquia (Medellín – Colombia) and Hamburg and received his MD-PhD at the University of Hamburg.
Nov 16, 2022 · The clinical examination revealed a motor neuron syndrome with a clear bilateral wasting of the hand muscles, a diffuse atrophy of the shoulder and calf muscles, and a weakness of the arms, fingers, hips, and feet. Deep tendon reflexes were symmetrically briskly hyperactive.
There is growing evidence that promising biomarkers of inflammation in Alzheimer´s disease (AD) and other neurodegenerative diseases correlate strongest to levels of tau or neurofilament, indicating an inflammatory response to neuronal damage or death.
SUMMARY. Microglia are crucial for maintaining brain health and neuron function. Here, we report that microglia establish connections with neurons using tunneling nanotubes (TNTs) in both physiological and patho-logical conditions. These TNTs facilitate the rapid exchange of organelles, vesicles, and proteins.
