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    • Andrew DeLuca Died When Someone Stabbed Him. Season 17, Episode 7 - "Helplessly Hoping" Andrew DeLuca (Giacomo Gianniotti) became one of Meredith’s love interests, and he was in a constant battle with his mental health, showing signs of mania just like his father.
    • Derek Shepherd Died After A Car Accident. Season 11, Episode 21 - "How To Save A Life" One of the saddest and also most criticized Grey's Anatomy deaths is Derek Shepherd’s (Patrick Dempsey).
    • Samuel Norbert Avery Died At Birth. Season 11, Episode 11 - "All I Could Do Was Cry" One of the saddest episodes on Grey's Anatomy came in season 11. This death in Grey's was not to a long-standing cast member.
    • Mark Sloan Died In A Plane Crash. Season 9, Episode 2 - "Remember The Time" Another character who dies in Grey's Anatomy as a consequence of the infamous plane crash is Mark Sloan (Eric Dane).
    • Denny Duquette (Season 2, Episode 27) Love makes people do crazy things; but, unfortunately cutting L-Vad wires, breaking the law, and Izzie almost losing her job couldn’t save Denny Duquette from death.
    • George O’Malley (Season 5, Episode 24) The world collectively gasped when George was revealed to be on the other side of the elevator doors, dressed in his Army uniform, ready to guide Izzie (Katherine Heigl) to the afterlife.
    • Derek Shepard (Season 11, Episode 24) There wasn’t enough wine in the world to prepare “Grey’s” fans for Derek Shepard’s untimely passing. A day that began with McDreamy saving a family, ended in his death as the incapacitated neurosurgeon described the missing steps in his own emergency intake and surgery.
    • Mark Sloan (Season 9, Episode 1) Did McSteamy really have to die? If you compare him to Lexie — who died an episode earlier — he made it through the plane crash unscathed, only to succumb to his injuries and be pulled off life support in the dramatic Season 9 premiere.
  2. Mar 14, 2024 · Typically, a major character’s untimely demise happens during a finale of Grey’s Anatomy. But Derek Shepherd’s was a few episodes before in season 11—and no one saw it coming.

    • Annabel Gutterman
    • who died on 'grey's anatomy' death and dying life and dying1
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  3. Feb 14, 2019 · Here are all the 'Grey's Anatomy' cast members whose characters have died over the years, including Derek Shepherd, Mark Sloan, George O'Malley, Lexie Grey, and more.

    • 3 min
  4. May 30, 2024 · Throughout the past 20 seasons of 'Grey's Anatomy,' viewers have mourned the loss of many fan-favorite characters. Here's a look at some of the show's most shocking — and heartbreaking —...

    • who died on 'grey's anatomy' death and dying life and dying1
    • who died on 'grey's anatomy' death and dying life and dying2
    • who died on 'grey's anatomy' death and dying life and dying3
    • who died on 'grey's anatomy' death and dying life and dying4
    • who died on 'grey's anatomy' death and dying life and dying5
  5. May 27, 2021 · Which characters left or died on Grey's Anatomy in Season 17? Look back at every Grey's Anatomy Season 17 death & exits, including Jackson Avery & Andrew DeLuca.

  6. Mar 12, 2021 · During Thursday's two-hour crossover premiere event with Station 19, the doctors of Grey Sloan Memorial fought hard to save the life of Dr. Andrew DeLuca (Giacomo Gianniotti) — who was...

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