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1. • • The laboratory rat was the first mammal domesticated for research purposes. It is descended from wild Norway rats, Rattus norvegicus, which despite their name likely originated in Asia. Exceptionally adaptable, these rodents now inhabit almost all environments on Earth, especially near human settlements where they are often seen as pests.
     elifesciences.org/articles/50651

     The Natural History of Model Organisms: The Norway rat, from ...

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   Are humans laboratory rats?

   • Although narrow-entry, randomized, placebo-controlled trials based on preplanned deaths and overall survival may be the gold standard in the laboratory today, human beings are not laboratory rats. Sound scientific research can be done without lethality as a planned endpoint. ■

   What Do Humans and Laboratory Rats Have in Common?

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   What is a laboratory rat?

   • Laboratory rats or lab rats are strains of the rat subspecies Rattus norvegicus domestica (Domestic Norwegian rat) which are bred and kept for scientific research. While less commonly used for research than laboratory mice, rats have served as an important animal model for research in psychology and biomedical science. [ 1 ]

   Laboratory rat - Wikipedia

   en.wikipedia.org/wiki/Laboratory_rat

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   Why are laboratory rats so popular?

   • First domesticated from wild Norway rats over 170 years ago (Richter, 1959), today laboratory rats owe their popularity as a model organism largely due to their widespread availability, low breeding costs, short reproductive cycle and ability to thrive in captive environments.

   The Natural History of Model Organisms: The Norway rat, from an obno…

   elifesciences.org/articles/50651

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   Are laboratory rats still needed?

   • The need for laboratory rats has increased in the past 60 years and will likely continue to grow. In 1966, the Animal Welfare Act created stipulations for using large mammals such as monkeys or dogs in research. The law was a response to pet owners whose animals had been stolen and sold to laboratories.

   The History of the Lab Rat - Discover Magazine

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   Where did rat research come from?

   • The rat found early use in laboratory research in five areas: W. S. Small suggested that the rate of learning could be measured by rats in a maze; a suggestion employed by John B. Watson for his Ph.D. dissertation in 1903. [ 4 ]

   Laboratory rat - Wikipedia

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   How many rats are in a lab?

   • Because the law specifically does not include rats, government officials do not inspect laboratories that use and house rats. Without government oversight, it's difficult to determine how many rats are in the U.S. labs. One study estimated as many as 115 million rats are being used for research.

   The History of the Lab Rat - Discover Magazine

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3. en.wikipedia.org › wiki › Laboratory_ratLaboratory rat - Wikipedia

   en.wikipedia.org › wiki › Laboratory_rat

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   The albino laboratory rat with its red eyes and white fur is an iconic model organism for scientific research in a variety of fields. Laboratory rats or lab rats are strains of the rat subspecies Rattus norvegicus domestica (Domestic Norwegian rat) which are bred and kept for scientific research.

4. www.smithsonianmag.com › science-nature › historyThe History of the Lab Rat Is Full of Scientific Triumphs and ...

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   Feb 27, 2019 · For decades, lab rats and mice have been used to make great scientific and medical advances, from cancer drugs and HIV antiretrovirals to the yearly flu vaccine.

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6. www.discovermagazine.com › the-sciences › theThe History of the Lab Rat - Discover Magazine

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   Feb 11, 2023 · Why are they running through mazes, pushing levers to receive treats or being placed into rat-sized guillotines? The history of the lab rat dates back centuries, and the sequencing of the rat genome in the early 2000s means rat research is providing more insight than ever.

   • Author: Emilie Le Beau Lucchesi

7. www.atlasobscura.com › articles › the-doomed-mouseThe Doomed Mouse Utopia That Inspired the ‘Rats of NIMH’

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   Sep 14, 2016 · As Edmund Ramsden and Jon Adams detail in a paper, “ Escaping the Laboratory: The Rodent Experiments of John B. Calhoun & Their Cultural Influence,” Calhoun spent his childhood traipsing around...

   • Author: Cara Giaimo

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     Behind the Scenes of Disney XD's Lab Rats

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     The Life Of A Professional Lab Rat

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     The Laboratory Rat: A Natural History. M. Berdoy. Oxford University. FULL & HD VERSION

     11 Jun 2017

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9. cosmosmagazine.com › science › mathematicsThe Calhoun rodent experiments: the real-life rats of NIMH

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   Oct 22, 2021 · Calhoun calculated that his pen of wild Norway rats (or brown rats, aka Parisian rats, Hanover rats, street rats, common rats, sewer rats, wharf rats… in essence, “rats” as you know them ...

10. ascopost.com › issues › august-15-2014What Do Humans and Laboratory Rats Have in Common?

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    Aug 15, 2014 · Although narrow-entry, randomized, placebo-controlled trials based on preplanned deaths and overall survival may be the gold standard in the laboratory today, human beings are not laboratory rats. Sound scientific research can be done without lethality as a planned endpoint. —­­Donald M. Gleason, MD Clinical Professor, Urology (retired)

11. elifesciences.org › articles › 50651The Natural History of Model Organisms: The Norway rat, from ...

    elifesciences.org › articles › 50651

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    Jan 17, 2020 · The laboratory rat was the first mammal domesticated for research purposes. It is descended from wild Norway rats, Rattus norvegicus, which despite their name likely originated in Asia.