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AdApoptosis Assays - HCS Apoptosis Analysis - By Invitrogen™
Invitrogen apoptosis assays. Detect apoptosis. DNA fragmentation. Multiplexable. Assays for flow cytometry, microscopy, high-content analysis & microplate.
- Microscopy Assays
Caspase activity, DNA fragmentation
Annexin V staining
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TUNEL assays for imaging & HCS
Optimized assays
- Caspase Assays
Assays for imaging & microplates
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- DNA morphology
TUNEL assays for imaging & HCS
Study chromatin condensation
- Microscopy Assays
Host Cell including HEK293, HeLa, CHO, U2OS etc.Plasmid/lentivirus Transduction. Creative Biogene provides molecular biology reagents/Dna/Rna/Stable Cell line, Learn more
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GFP, RFP, Luciferase cell lines
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CRISPR-Cas9 related services
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Fast turnaround/high-quality/cost-effectiveness of apoptosis&cell death analysis service. Screening assays to assess apoptosis factors. Comprehensive experimental verification.
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Jun 6, 2017 · Because apoptosis can prevent cancer, and because problems with apoptosis can lead to some diseases, apoptosis has been studied intensely by scientists since the 1990s. Function of Apoptosis. Apoptosis is an important evolutionary adaptation because it allows organisms to destroy their own cells. At first glance, that may sound like a terrible ...
Apoptosis (from Ancient Greek: ἀπόπτωσις, romanized:apóptōsis, lit. 'falling off') is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast. [ 1 ] Biochemical events lead to characteristic cell changes (morphology) and death. [ 2 ]
Sep 13, 2024 · Once apoptosis begins, a series of chemical changes happen that cause the cell to break into many small parts. The cell sends signals to other cells, called phagocytes (a type of white blood cell), telling them to consume the cell parts. At the same time, the dying cell also sends signals that lessen inflammation and help nearby tissues heal.
Jan 4, 2024 · Apoptosis, the first regulated form of cell death discovered in mammalian cells, is executed by caspase-3/7, which are dormant in living cells but become activated by upstream caspase-8 or caspase-9 in responding to extracellular cytokines or intracellular stress signals, respectively. The same cell death-inducing cytokines also cause ...
Jun 19, 2007 · In most cells, apoptosis triggers usually lead to the activation of caspases, which ultimately mediate the autodestruction of the cell. ... Goeddel DV . A novel domain within the 55 kd TNF ...
- Guangwu Xu, Yufang Shi
- 2007
Cells that die as a result of acute injury typically swell and burst. They spill their contents all over their neighbors—a process called cell necrosis —causing a potentially damaging inflammatory response. By contrast, a cell that undergoes apoptosis dies neatly, without damaging its neighbors. The cell shrinks and condenses.
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Apoptosis, or programmed cell death, begins when enzymes called caspases start a controlled demolition process within the cell. This review covers the sequence of known steps involved in apoptosis.
