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AdApoptosis Assays | HCS Apoptosis Analysis | By Invitrogen™
Invitrogen apoptosis assays. Detect apoptosis. DNA fragmentation. Multiplexable. Assays for flow cytometry, microscopy, high-content analysis & microplate.
- Microscopy Assays
Caspase activity, DNA fragmentation
Annexin V staining
- Annexin V Staining
Detect apoptosis with annexin V
Alexa fluor conjugates
- DNA Fragmentation
TUNEL assays for imaging & HCS
Study chromatin condensation
- High-content assays
Optimized & automated
Detect apoptosis with a TUNEL assay
- TUNEL Assays
TUNEL assays for imaging & HCS
Optimized assays
- Caspase Assays
Assays for imaging & microplates
See the Selection Guide
- Microscopy Assays
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Jun 6, 2017 · Apoptosis is a process that occurs in multicellular when a cell intentionally “decides” to die. This often occurs for the greater good of the whole organism, such as when the cell’s DNA has become damaged and it may become cancerous. Apoptosis is referred to as “programmed” cell death because it happens due to biochemical instructions ...
Apoptosis (from Ancient Greek: ἀπόπτωσις, romanized:apóptōsis, lit. 'falling off') is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast. [ 1 ] Biochemical events lead to characteristic cell changes (morphology) and death. [ 2 ]
May 14, 2022 · Apoptosis triggered by external signals Figure 3.20.2 Apoptosis by external trigger. Fas and the TNF receptor are integral membrane proteins with their receptor domains exposed at the surface of the cell; Binding of the complementary death activator (FasL and TNF respectively) transmits a signal to the cytoplasm that leads to the activation of ...
Sep 7, 2024 · apoptosis, in biology, a mechanism that allows cells to self-destruct when stimulated by the appropriate trigger. Apoptosis can be triggered by mild cellular injury and by various factors internal or external to the cell; the damaged cells are then disposed of in an orderly fashion. As a morphologically distinct form of programmed cell death ...
Mar 20, 2024 · Apoptosis is a highly regulated and controlled process that unfolds in distinct stages, each characterized by specific cellular changes and biochemical events. Initiation: Internal or external signals trigger the apoptosis pathways. Early Apoptosis: Key indicators include cell shrinkage, chromatin condensation, and membrane blebbing.
Apr 8, 2024 · Apoptosis is a physiological process in which cell death is brought about through a regulated sequence of events. It leads to the programmed removal of targeted cells, without harming nearby cells. Defects of this process play an important role in a variety of diseases. This article shall consider the process of apoptosis, its regulation, and ...
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Jan 1, 2019 · One notable feature of apoptosis is it exerts its effects mainly through action of a type of serine proteases known as caspases. A death signals are relayed through signaling pathways which ultimately lead to activation of caspases responsible for the execution of cell destruction . Both external and internal stimuli, coupled to extrinsic and ...
