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1. • Erythrocytes

     

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     • Cyanide in blood is almost exclusively localized to the erythrocytes, whereas thiocyanate is confined to plasma (Lundquist and Sorbo 1989); thus, some researchers recommend analysis of erythrocytes (McMillan and Svoboda 1982; Sano et al. 1992).
     www.ncbi.nlm.nih.gov/books/NBK600912/

     ANALYTICAL METHODS - Toxicological Profile for Cyanide - NCBI ...

2. People also ask

   Where is hydrogen cyanide found?

   • The distribution of hydrogen cyanide following absorption is rapid and widespread (4). Following ingestion, cyanide is found in the stomach, with lesser amounts found in the spleen, blood, liver, brain, and kidney; it is found in the lung, blood, brain and kidneys following inhalation (3, 4).

   Hydrogen Cyanide: toxicological overview - GOV.UK

   www.gov.uk/government/publications/hydrogen-cyanide-properties-incident-management-and-toxicology/hydrogen-cyanide-toxicological-overview

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   Does cyanide accumulate in blood?

   • Cyanide does not accumulate in blood and tissues following chronic oral exposure. In a study with rats administered hydrogen cyanide in the diet at <10.4 mg CN − /kg/day for 2 years, virtually no cyanide was found in plasma or kidneys (Howard and Hanzal 1955). Metabolism. See Section 3.4.5. Excretion.

   HEALTH EFFECTS - Toxicological Profile for Cyanide - NCBI Bookshelf

   www.ncbi.nlm.nih.gov/books/NBK600901/

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   How does cyanide absorb?

   • Cyanide absorbs quickly through the respiratory tract and mucous membranes as well as the gastrointestinal tract and skin. Signs and symptoms begin at blood cyanide concentrations of approximately 40 mol/L. In vivo, cyanide metabolism and neutralization involve a number of mechanisms.

   Cyanide Toxicity - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov/books/NBK507796/

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   How is cyanide metabolized in vivo?

   • In vivo, cyanide metabolism and neutralization involve a number of mechanisms. The most important of these is the detoxification of cyanide via rhodanese, an enzyme found abundantly in many tissues but in the liver and muscle particularly.

   Cyanide Toxicity - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov/books/NBK507796/

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   Where did cyanide come from?

   • Hydrogen cyanide was first isolated from Prussian blue dye in 1786, and cyanide first extracted from almonds around 1800. Cyanide can exist as a gas, hydrogen cyanide, a salt, potassium cyanide. Natural substances in some foods such as lima beans, almonds can release cyanide.

   Cyanide Toxicity - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov/books/NBK507796/

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   Why is cyanide poisoning so common?

   • People first used cyanide as a chemical weapon during World War I, and various dictators and terrorists have used it since then. Exposure to high levels of cyanide can result in cyanide poisoning, with fire being the most common source of exposure. About 35% of all fire victims have toxic levels of cyanide in their blood.

   Cyanide poisoning: Symptoms, causes, and treatment - Medical News T…

   www.medicalnewstoday.com/articles/cyanide-poisoning

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3. www.gov.uk › government › publicationsHydrogen Cyanide: toxicological overview - GOV.UK

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   Aug 14, 2024 · Following ingestion, cyanide is found in the stomach, with lesser amounts found in the spleen, blood, liver, brain, and kidney; it is found in the lung, blood, brain and kidneys following...

4. en.wikipedia.org › wiki › Cyanide_poisoningCyanide poisoning - Wikipedia

   en.wikipedia.org › wiki › Cyanide_poisoning

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   A blood diagnostic reported a lethal level of cyanide in his blood, but the body did not display any classic symptoms of cyanide poisoning, and no link to cyanide could be found in Urooj's social circle.

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6. www.ncbi.nlm.nih.gov › books › NBK600901HEALTH EFFECTS - Toxicological Profile for Cyanide - NCBI ...

   www.ncbi.nlm.nih.gov › books › NBK600901

   Blood cyanide increased to a peak of 110 nmol/mL at 3 hours after such a dose of linamarin or to 140 nmol/mL after amygdalin (Frakes et al. 1986b).

   • Published: 2006/07

7. www.ncbi.nlm.nih.gov › pmc › articlesA Review on Ingested Cyanide: Risks, Clinical Presentation ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Dec 11, 2018 · Once absorbed into the blood stream, cyanide equilibrates between the cyanide anion (CN −) and un-dissociated hydrogen cyanide (HCN) [12]. In this form (HCN), cyanide can easily cross the cell membrane and inhibit multiple enzymes including succinic dehydrogenase, superoxide dismutase, and cytochrome oxidase [12 – 14].

   • Author: Tara B. Hendry-Hofer, Patrick C. Ng, Patrick C. Ng, Alyssa E. Witeof, Sari B. Mahon, Matthew Brenner...

   • Publish Year: 2019

8. Videos

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     Rapid Visual Detection of Cyanide in Blood

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     Cyanide found in blood of Bangkok hotel victims | BBC News

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     How cyanide kills you in seconds?|cyanide poisoning

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9. litfl.com › cyanide-poisoning-cccCyanide Poisoning • LITFL • CCC Toxicology

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   Cyanide is concentrated 10 fold by RBCs, therefore whole blood levels give the best information on the potential for a toxic level. levels correlate with clinical severity >20 microM — symptomatic

10. www.ncbi.nlm.nih.gov › books › NBK507796Cyanide Toxicity - StatPearls - NCBI Bookshelf

    www.ncbi.nlm.nih.gov › books › NBK507796

    Feb 13, 2023 · Cyanide absorbs quickly through the respiratory tract and mucous membranes as well as the gastrointestinal tract and skin. Signs and symptoms begin at blood cyanide concentrations of approximately 40 mol/L. In vivo, cyanide metabolism and neutralization involve a number of mechanisms.

11. www.medicalnewstoday.com › articles › cyanide-poisoningCyanide poisoning: Symptoms, causes, and treatment

    www.medicalnewstoday.com › articles › cyanide-poisoning

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    Jan 30, 2024 · Cyanides refer to any compounds that comprise the carbon-nitrogen (C-N) bond in their structure. Cyanide is a fast acting deadly chemical that many people know to be a poison. It can exist as...